Study Results
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Basic Information
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COMPLETED
PHASE2
45 participants
INTERVENTIONAL
2009-01-31
2012-08-31
Brief Summary
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Magnetic resonance imaging (MRI) has proved beneficial for presenting anatomy for regional anaesthesia and to demonstrate spread of local anaesthetic.
A new axillary plexus block with a triple injection (1), combining a short axillary catheter method with a transarterial axillary block, is now being evaluated with a 3 Tesla MRI. In this study, the investigators are investigating MR visualisation of three different block techniques and compare the clinical efficacy of the techniques, with the MR findings.
Patients \& Methods:
After obtaining approval of the protocol from the regional ethical committee, 3 x 15 adult patients, scheduled for hand surgery, were included in a randomised, blinded prospective study.
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Detailed Description
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In all patients a short axillary plexus catheter is positioned close to the median nerve using nerve stimulator.
Technique 1 = 40 ml in catheter Technique 2 = 30 ml behind and 10 ml in front of the brachial artery (BA) Technique 3 = 20 ml behind, 10ml in front of the BA and 10 ml in catheter
Clinical High Field MRI (3T) scanner has simplified the recognition of brachial plexus nerves in the axilla. After injection of local anaesthetic (LA), the identification of the nerve structures is nevertheless difficult. When all nerves are surrounded of LA in the axilla (MRI), it seems to be associated with a clinical complete brachial plexus block
Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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Arm 1: catheter injection
40 ml of LA through the catheter
Active Comparator: Arm 1: catheter injection
Arm 2: transarterial injection
30 ml deep and 10 ml superficial to the artery
Active Comparator: Arm 2: transarterial injection
Arm 3: catheter and transarterial injection
20 + 10 ml transarterial block and 10 ml through the catheter
Active Comparator: Arm 3: catheter and transarterial injection
Interventions
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Active Comparator: Arm 1: catheter injection
Active Comparator: Arm 2: transarterial injection
Active Comparator: Arm 3: catheter and transarterial injection
Eligibility Criteria
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Inclusion Criteria
* ASA 1 - 2
* Weight from 50 - 95 kg
* MR compatible, suitable
Exclusion Criteria
* Reaction to LA
18 Years
75 Years
ALL
No
Sponsors
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Oslo University Hospital
OTHER
Diakonhjemmet Hospital
OTHER
Responsible Party
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Trygve Kjelstrup, MD
Section manager
Principal Investigators
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Trygve TK Kjelstrup, MD
Role: PRINCIPAL_INVESTIGATOR
Diakonhjemmet Sykehus, University of Oslo
Øivind ØK Klaastad, PhD, MD
Role: STUDY_DIRECTOR
Rikshospitalet, Dep. of Anesthesiology, Oslo University Hospital
Locations
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The Intervention Centre, Rikshospitalet, Oslo University Hospital
Oslo, , Norway
Countries
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References
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Kjelstrup T, Hol PK, Courivaud F, Smith HJ, Rokkum M, Klaastad O. MRI of axillary brachial plexus blocks: a randomised controlled study. Eur J Anaesthesiol. 2014 Nov;31(11):611-9. doi: 10.1097/EJA.0000000000000122.
Related Links
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The Intervention Centre
Other Identifiers
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S-04115
Identifier Type: -
Identifier Source: org_study_id
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