Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers

NCT ID: NCT01449097

Last Updated: 2011-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2011-11-30

Brief Summary

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The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers. The investigators hypothesize that the Adductor-Canal-Blockade results in a lesser reduction of the quadriceps muscle strength compared to the femoral nerve block.

Detailed Description

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Conditions

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Muscle Strength Healthy Volunteers

Keywords

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Adductor-Canal-blockade, human volunteers, US-guided nerve block femoral nerve block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Adductor-Canal-Blockade

Group Type EXPERIMENTAL

Adductor-Canal-Blockade

Intervention Type PROCEDURE

US-guided Adductor-Canal-blockade with Ropivacaine

The femoral nerve block

Group Type ACTIVE_COMPARATOR

The femoral nerve block

Intervention Type PROCEDURE

US-guided femoral nerve block with ropivacaine

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type PROCEDURE

US-guided Adductor-Canal-Blockade/femoral nerve block with saline

Interventions

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Adductor-Canal-Blockade

US-guided Adductor-Canal-blockade with Ropivacaine

Intervention Type PROCEDURE

The femoral nerve block

US-guided femoral nerve block with ropivacaine

Intervention Type PROCEDURE

Placebo

US-guided Adductor-Canal-Blockade/femoral nerve block with saline

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* written informed consent
* ASA 1
* BMI \> 18 og \< 25

Exclusion Criteria

* Can not cooperate to the exam
* Do not speak or understand Danish
* Drug allergy
* Alcohol or drug abuse
* Daily consumption of analgetics on prescription
* Any drug intake within the last 48 hours
* Neuromuscular defects in the femoral nere, the obturator nerve or the muscles of the thigh.
* Previous surgery or trauma to the lower limb
* Diabetes Mellitus
* Intake of steroids, except steroids for inhalation
* Physical exercise within the last 24 hours prior to Day 1 and 2 of the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Pia Jaeger

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pia Jæger, MD

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Department of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Jaeger P, Nielsen ZJ, Henningsen MH, Hilsted KL, Mathiesen O, Dahl JB. Adductor canal block versus femoral nerve block and quadriceps strength: a randomized, double-blind, placebo-controlled, crossover study in healthy volunteers. Anesthesiology. 2013 Feb;118(2):409-15. doi: 10.1097/ALN.0b013e318279fa0b.

Reference Type DERIVED
PMID: 23241723 (View on PubMed)

Other Identifiers

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SM2-PJ-11

Identifier Type: -

Identifier Source: org_study_id