Prospective Randomized Trial of Navigated and Conventional TKA

NCT ID: NCT01022099

Last Updated: 2009-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2008-12-31

Brief Summary

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Evaluation of the component position and kinematics after navigated and conventional Total Knee Arthroplasty.

Detailed Description

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1. Component position, kinematics After skin closure lateral x-rays were done in different flexion angles in order to evaluate the kinematic behaviour of the TKA.

A full-length standing and a lateral radiograph as well as CT scans of the hip, knee and ankle joint were performed 5 to 7 days postoperatively before discharge.
2. clinical outcome Patient sociodemographic and anamnestic data were collected. The written interview was complemented by the EuroQol questionnaire (release EQ-5D) and the assessment of the patients' functional status (Knee Society Score) one week before surgery and 18 to 24 month after surgery.

Conditions

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Osteoarthritis of the Knee

Keywords

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Total Knee Arthroplasty Navigation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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navigated TKA

Group Type ACTIVE_COMPARATOR

Implantation of a Total Knee Arthroplasty

Intervention Type PROCEDURE

In all patients a cemented, unconstrained, cruciate-retaining TKA with a rotating platform (ScorpioTM PCS, Stryker Orthopaedics, Mahwah, NJ) was implanted. No patellar resurfacing was performed. A medial parapatellar approach with a femur-first preparation was done in all cases.

The Stryker Navigation System, Knee Navigation Software V3.1 (Stryker Orthopaedics, Mahwah, NJ) was used for computer-assisted implantation.

The conventional implantation was performed with femoral intramedullary and tibial extramedullary standard alignment guides.

conventional TKA

Group Type OTHER

Implantation of a Total Knee Arthroplasty

Intervention Type PROCEDURE

In all patients a cemented, unconstrained, cruciate-retaining TKA with a rotating platform (ScorpioTM PCS, Stryker Orthopaedics, Mahwah, NJ) was implanted. No patellar resurfacing was performed. A medial parapatellar approach with a femur-first preparation was done in all cases.

The Stryker Navigation System, Knee Navigation Software V3.1 (Stryker Orthopaedics, Mahwah, NJ) was used for computer-assisted implantation.

The conventional implantation was performed with femoral intramedullary and tibial extramedullary standard alignment guides.

Interventions

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Implantation of a Total Knee Arthroplasty

In all patients a cemented, unconstrained, cruciate-retaining TKA with a rotating platform (ScorpioTM PCS, Stryker Orthopaedics, Mahwah, NJ) was implanted. No patellar resurfacing was performed. A medial parapatellar approach with a femur-first preparation was done in all cases.

The Stryker Navigation System, Knee Navigation Software V3.1 (Stryker Orthopaedics, Mahwah, NJ) was used for computer-assisted implantation.

The conventional implantation was performed with femoral intramedullary and tibial extramedullary standard alignment guides.

Intervention Type PROCEDURE

Other Intervention Names

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ScorpioTM PCS Stryker Navigation System Stryker Knee Navigation Software V3.1

Eligibility Criteria

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Inclusion Criteria

* primary or secondary osteoarthritis of the knee
* indication to TKA
* a mechanical axis between 20° varus and 5° valgus
* signed informed consent

Exclusion Criteria

* previous hemi- or total arthroplasty
* severe instability that could not be treated with an unconstrained, cruciate-retaining TKA
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Technische Universität Dresden

OTHER

Sponsor Role lead

Responsible Party

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Dresden University of Technology

Principal Investigators

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Klaus-Peter Günther, MD, PhD

Role: STUDY_DIRECTOR

Orthopaedic Department, University Hospital Dresden

Locations

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University Hospital Dresden, Orthopaedic Department

Dresden, , Germany

Site Status

Countries

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Germany

References

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Lutzner J, Krummenauer F, Wolf C, Gunther KP, Kirschner S. Computer-assisted and conventional total knee replacement: a comparative, prospective, randomised study with radiological and CT evaluation. J Bone Joint Surg Br. 2008 Aug;90(8):1039-44. doi: 10.1302/0301-620X.90B8.20553.

Reference Type RESULT
PMID: 18669959 (View on PubMed)

Beyer F, Pape A, Lutzner C, Kirschner S, Lutzner J. Similar outcomes in computer-assisted and conventional total knee arthroplasty: ten-year results of a prospective randomized study. BMC Musculoskelet Disord. 2021 Aug 18;22(1):707. doi: 10.1186/s12891-021-04556-3.

Reference Type DERIVED
PMID: 34407776 (View on PubMed)

Harman MK, Banks SA, Kirschner S, Lutzner J. Prosthesis alignment affects axial rotation motion after total knee replacement: a prospective in vivo study combining computed tomography and fluoroscopic evaluations. BMC Musculoskelet Disord. 2012 Oct 23;13:206. doi: 10.1186/1471-2474-13-206.

Reference Type DERIVED
PMID: 23088451 (View on PubMed)

Lutzner J, Krummenauer F, Gunther KP, Kirschner S. Rotational alignment of the tibial component in total knee arthroplasty is better at the medial third of tibial tuberosity than at the medial border. BMC Musculoskelet Disord. 2010 Mar 25;11:57. doi: 10.1186/1471-2474-11-57.

Reference Type DERIVED
PMID: 20338042 (View on PubMed)

Other Identifiers

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KneeNavy

Identifier Type: -

Identifier Source: org_study_id