Detecting Early Myocardial Infiltration w/Amyloid & Light Chain Deposition Disease in Multiple Myeloma Subjects

NCT ID: NCT01018927

Last Updated: 2017-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Study Completion Date

2017-05-30

Brief Summary

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The purpose of this study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma. Cardiac amyloidosis is a medical disorder that decreases heart function.

Detailed Description

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The purpose is to investigate the use of multiple newer CMR techniques for early evaluation of cardiac amyloidosis in multiple myeloma.

Conditions

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Multiple Myeloma

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Additional MRI images

Prospective review of 100 CMR studies performed on multiple myeloma patients referred for cardiac evaluation by MRI. Three additional MRI images will be performed to determine the role of cardiac MR (CMR) in detecting features of early myocardial infiltration

Administering three additional MRI images

Intervention Type DEVICE

Three additional MRI images to determine the role of cardiac MR (CMR) in detecting features of early myocardial infiltration

Interventions

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Administering three additional MRI images

Three additional MRI images to determine the role of cardiac MR (CMR) in detecting features of early myocardial infiltration

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* All races and ethnic groups
* Male and female ages 18-80 years of age
* History of multiple myeloma
* CMR study for evaluation for cardiac amyloidosis

Exclusion Criteria

* Pregnant women
* Subject with a metallic or electronic or other device that could be affected by the magnet
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Siemens Molecular Imaging

INDUSTRY

Sponsor Role collaborator

University of Arkansas

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tarun Pandey

Role: PRINCIPAL_INVESTIGATOR

University of Arkansas for Medical Sciences (UAMS)

Locations

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University or Arkansas for Medical Sciences (UAMS)

Little Rock, Arkansas, United States

Site Status

Countries

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United States

Other Identifiers

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110104

Identifier Type: -

Identifier Source: org_study_id

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