Evaluation of a XIENCE V® Endoprothesis Used for Coronary Angioplasty, for LPPR (List of Reimbursable Products and Services) Indications in Patients Monitored for 2 Years in France

NCT ID: NCT00987506

Last Updated: 2012-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1165 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-06-30

Study Completion Date

2011-12-31

Brief Summary

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The objective of this study is to prepare elements of response to the Haute Autorité de Santé (High Health Authority) of France, which is expecting data relating to the routine use of XIENCE V® endoprothesis within the 5 years following its marketing.

Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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XIENCE V®

Participants receiving XIENCE V® EESS

XIENCE V®

Intervention Type DEVICE

Participants with placement of a XIENCE V® EESS

Interventions

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XIENCE V®

Participants with placement of a XIENCE V® EESS

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

All patients enrolled in the study must :

* be at least 18;
* be covered by Social Security
* agree to be enrolled in the study (sign the informed consent after reading the information letter).

In addition, the Xience V endoprothesis implantation must be performed following the LPPR indications here under :

Treatment of coronary heart disease attributable to de novo lesions (reference vessel with a 2.5 to 3.5 mm) of native coronary arteries, solely in the following groups of patients :

* patients with diabetes ;
* lesions of small vessels (diameter \< 3 mm);
* long lesions (longer than 15 mm) ;
* stenosis of proximal anterior intraventricular septum .

The use of the Xience V stent is limited to one per patient, except :

* in case of acute occlusive dissection where three stents, maximum, may be covered ;
* for the pluritroncular diabetic patient, in case a bypass is contra-indicated : a stent per artery, with a limit of three per patient, may be covered.

Exclusion Criteria

* Pregnant women
* Patients with:

* a non cardiac vital prognosis endangered during the year following the implantation ;
* less than 72 hours myocardial infarction ;
* lower left ventricular ejection fraction \< 30 % ;
* an allergy to the platelets antiaggregant treatment, to heparin, chrome cobalt alloy, or to the angiography contrast medium ;
* a stenosis of the unprotected common trunk;
* a lesion with calcifications that cannot be pre-dilated;
* a thrombus that can be detected by angiography on the lesion to be treated ;
* an intra-stent re-stenosis.

Are also excluded :

* patients having had an angioplasty with implantation of an endoprothesis on the same vessel;
* patients having had an angioplasty with implantation of an endoprothesis during the 6 previous months ;
* Patients unable to keep a treatment associating aspirin and thiénopyridines for at least 6 months;
* Patients residing abroad or who cannot be monitored according to the modalities of the study ;
* Patients unable to give on their own free will their informed consent ; On the other hand, in absence of clinical validation, the other sub-groups of at risk patients (notably bifurcation lesions and pluritroncular lesions) cannot be considered , taken alone, as indications for the use of Xience V.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Didier Blanchard, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital Européen Georges-Pompidou

Locations

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Clinique De L'Europe

Amiens, , France

Site Status

CH Universitaire

Angers, , France

Site Status

Hopital Prive D'Antony

Antony, , France

Site Status

Clinique La Casamance - UCV

Aubagne, , France

Site Status

Clinique La Casamance-Vista

Aubagne, , France

Site Status

Clnique Rhone-Durance

Avignon, , France

Site Status

Clinique LaFourcade

Bayonne, , France

Site Status

CH Jean Minjoz

Besançon, , France

Site Status

Polyclinique Du Bois Bernard

Bois-Bernard, , France

Site Status

CH Jacques Coeur

Bourges, , France

Site Status

Hôpital de la Cavale Blanche-CHU

Brest, , France

Site Status

CH Prive Saint-Martin

Caen, , France

Site Status

Hopital Albert Schweitzer

Colmar, , France

Site Status

Clinique Des Cedres

Cornebarrieu, , France

Site Status

Polyclinique Louis Pasteur

Essey-lès-Nancy, , France

Site Status

Centre Cardiologique D'Evecquemont

Évecquemont, , France

Site Status

CH Saint Louis

La Rochelle, , France

Site Status

CH DE Lagny- Marne La Valee

Lagny-sur-Marne, , France

Site Status

CMC De Parly II

Le Chesnay, , France

Site Status

Polyclinique Du Bois

Lille, , France

Site Status

CH ST Joseph St. Luc

Lyon, , France

Site Status

Clinique Generale De Marignane

Marignane, , France

Site Status

Centre Cardio-Vasculaire Valmante

Marseille, , France

Site Status

CH Prive Beauregard

Marseille, , France

Site Status

Institut Hospitalier Jacques Cartier

Massy, , France

Site Status

Clinique Les Fontaines

Melun, , France

Site Status

Clinique Du Millenaire

Montpellier, , France

Site Status

Hopital Emile Muller

Mulhouse, , France

Site Status

NCN-Nouvelles Cliniques Nantaises

Nantes, , France

Site Status

Clinique Ambroise Pare

Neuilly-sur-Seine, , France

Site Status

Hopital Prive Les Franciscaines

Nîmes, , France

Site Status

Polyclinique les Fleurs

Ollioules, , France

Site Status

Institut Mutualiste Montsouris

Paris, , France

Site Status

Association Clinique Bizet

Paris, , France

Site Status

Hôpital Européen Georges Pompidou

Paris, , France

Site Status

Clinique Saint-Pierre

Perpignan, , France

Site Status

CH General Marechal Joffre

Perpignan, , France

Site Status

Clinicque St. Martin

Pessac, , France

Site Status

Polyclinique de Poitiers

Poitiers, , France

Site Status

Hopital Claude Gallien - ICPS

Quincy-sous-Sénart, , France

Site Status

Polyclinique St. Laurent

Rennes, , France

Site Status

Hopital Pontchaillou

Rennes, , France

Site Status

Hopital Charles Nicolle-CHU

Rouen, , France

Site Status

C.M.C.O De La Cote D'Opale

Saint Martin Les Boulogne, , France

Site Status

Centre Cardilogique du Nord

Saint-Denis, , France

Site Status

Clinique De L'Orangerie

Strasbourg, , France

Site Status

Hopital Foch

Suresnes, , France

Site Status

Clinique De L'Ormeau-CCV Des Pyrenees

Tarbes, , France

Site Status

Clinique Pasteur

Toulouse, , France

Site Status

Clinque Pasteur

Toulouse, , France

Site Status

Clinique Pasteur

Toulouse, , France

Site Status

Hopital De Rangueil - CHU

Toulouse, , France

Site Status

Clinique Saint Gatien

Tours, , France

Site Status

Centre Hospitalier De Valenciennes

Valenciennes, , France

Site Status

Polyclinique De Vauban

Valenciennes, , France

Site Status

Hopital de Brabois_CHU Nancy

Vandœuvre-lès-Nancy, , France

Site Status

CH Bretagne Atlantique

Vannes, , France

Site Status

Clinique Du Tonkin

Villeurbanne, , France

Site Status

Countries

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France

Other Identifiers

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F330702

Identifier Type: -

Identifier Source: org_study_id

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