A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure
NCT ID: NCT00950508
Last Updated: 2014-11-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
183 participants
INTERVENTIONAL
1998-06-30
2009-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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High volume plasma exchange
3 successive plasma exchanges over 3 days
High volume plasma exchange
3 high volume plasma exchanges over 3 days
Standard medical treatment
Standard medical treatment
Standard medical treatment
Standard medical treatment
Standard medical treatment
Interventions
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High volume plasma exchange
3 high volume plasma exchanges over 3 days
Standard medical treatment
Standard medical treatment
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* primary non function liver graft or graft dysfunction
* known chronic liver disease
* known malignancies
* clinical suspicion of brain death
18 Years
ALL
No
Sponsors
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Rigshospitalet, Denmark
OTHER
Responsible Party
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Dr. Fin Stolze Larsen
Senior consultant
Principal Investigators
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Fin S Larsen, PhD,Dr.M.Sc
Role: STUDY_CHAIR
Rigshospitalet, Denmark
Locations
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Department of Hepatology, Rigshospitalet
Copenhagen, DK, Denmark
Department of Transplantation and Liver Surgery, Helsinki University Hospital
Helsinki, , Finland
Institute of Liver Studies, King's College Hospital
London, , United Kingdom
Countries
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References
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Larsen FS, Schmidt LE, Bernsmeier C, Rasmussen A, Isoniemi H, Patel VC, Triantafyllou E, Bernal W, Auzinger G, Shawcross D, Eefsen M, Bjerring PN, Clemmesen JO, Hockerstedt K, Frederiksen HJ, Hansen BA, Antoniades CG, Wendon J. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial. J Hepatol. 2016 Jan;64(1):69-78. doi: 10.1016/j.jhep.2015.08.018. Epub 2015 Aug 29.
Other Identifiers
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EMPET-001
Identifier Type: -
Identifier Source: org_study_id
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