Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

18000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-01

Study Completion Date

2021-12-01

Brief Summary

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The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe, fulminating acute liver failure in the public hospitals of paris.

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Detailed Description

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Severe, fulminating acute liver failure is a rare but serious disease. The overall prognosis has improved in recent years thanks to advances in medical management and liver transplantation.

However, the epidemiology of this disease in France, the survival with or without liver transplantation of these patients and the factors that can influence this survival are not well known.

The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe, fulminating acute liver failure in the public hospitals of paris (APHP).

The data will come from the APHP Health Data Warehouse

Conditions

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Fulminating Hepatic Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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all patients diagnosed with a severe hepatic failure

Retrospective cohort using only data already entered in the Health data warehouse of the APHP (Public Paris Hospital)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age \> 15
* Severe liver failure or toxicants that may cause a liver failure Or
* (PR\<50% or INR \>1.5) And ALT \>250

Exclusion Criteria

* Patients with underlying chronic liver disease
* Patients with the conditions given by this following ICD (International Classification of Diseases) : B18 - E831 - K70 - K715 - K717 - K730- K731 - K732 - 738 - K74 - K753 - K758 - K760 - K761

Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No