High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure
NCT ID: NCT02719210
Last Updated: 2018-12-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
75 participants
INTERVENTIONAL
2016-01-01
2018-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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High Volume Plasma Exchange with Standard Treatment
High Volume Plasma Exchange
Standard Treatment
Standard Treatment is defined as anti raised Intra-cranial pressure
1. Elective positive pressure ventilation in hepatic encephalopathy grade 3 or 4 and in those with features of raised ICP (Intra-cranial pressure).
2. Mannitol
3. Hypertonic 3% Saline
Hypertonic 3% saline
Mannitol
Elective positive pressure ventilation
Interventions
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High Volume Plasma Exchange
Hypertonic 3% saline
Mannitol
Elective positive pressure ventilation
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. Refusal of consent or assent (annexure 3)
3. Liver resections with liver failure
4. Patients with clinical suspicion of irreversible brain injury
5. Patients with acute kidney injury
1 Year
18 Years
ALL
No
Sponsors
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Institute of Liver and Biliary Sciences, India
OTHER
Responsible Party
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Principal Investigators
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Dr Arti Pawaria, MD
Role: PRINCIPAL_INVESTIGATOR
Institute of Liver and Biliary Sciences
Locations
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Institute of liver and Biliary Sciences
New Delhi, National Capital Territory of Delhi, India
Countries
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Other Identifiers
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ILBS-ALF-02
Identifier Type: -
Identifier Source: org_study_id
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