Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis

NCT ID: NCT00939471

Last Updated: 2024-07-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-04-01

Study Completion Date

2010-05-01

Brief Summary

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A non-randomized, multi-center, prospective, clinical study intended to evaluate the safety and efficacy of balloon sinuplasty devices in pediatric patients with longstanding sinusitis following failed medical management.

Detailed Description

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Conditions

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Chronic Sinusitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Relieva™ Balloon Sinuplasty™ System

Balloon Dilation of sinus ostium

Group Type OTHER

Relieva™ Balloon Sinuplasty™ System

Intervention Type DEVICE

Balloon dilation will be performed using endoscopic equipment with video documentation capability.

Interventions

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Relieva™ Balloon Sinuplasty™ System

Balloon dilation will be performed using endoscopic equipment with video documentation capability.

Intervention Type DEVICE

Other Intervention Names

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Relieva

Eligibility Criteria

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Inclusion Criteria

1. Age \> 2 and \< 18 years
2. Both male and female patients eligible
3. Planned surgical intervention (i.e. endoscopic sinus surgery, adenoidectomy, sinus irrigation for obtaining a culture) recommended by PI, consented to by patient's legal guardian)
4. Longstanding sinusitis: \>3 mo symptoms OR 6 episodes/yr AND failed 2 courses antibiotics followed by positive CT scan

Exclusion Criteria

1. Extensive previous sinonasal surgery in target ostia
2. Cystic fibrosis
3. Extensive sinonasal osteoneogenesis
4. Sinonasal tumors or obstructive lesions
5. History of facial trauma that distorts sinus anatomy and precludes access to the sinus ostium
6. Ciliary dysfunction
7. For female patients of childbearing age: the patient is either pregnant or lactating
Minimum Eligible Age

2 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Acclarent

INDUSTRY

Sponsor Role collaborator

Integra LifeSciences Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hassan Ramadan, MD

Role: PRINCIPAL_INVESTIGATOR

West Virginia University

Locations

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West Virginia University

Morgantown, West Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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CPR01918

Identifier Type: -

Identifier Source: org_study_id

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