A Single Center Clinical Evaluation of Same Sitting Hybrid Revascularization: Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease

NCT ID: NCT00928356

Last Updated: 2020-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-10-14

Study Completion Date

2019-08-13

Brief Summary

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The primary objective of this study is to assess the safety and effectiveness of same sitting, simultaneous hybrid robotic assisted coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the treatment of obstructive multivessel coronary artery disease. A secondary objective is the assessment and standardization of optimal operator techniques and comparative study of patients undergoing CABG during study period.

Detailed Description

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The study population will consist of patients with multivessel coronary artery disease requiring CABG with suitable anatomy for combination CABG and PCI of non-bypassed arteries.

The primary endpoint of this feasibility study is a 30-day composite of major adverse clinical events including death, repeat revascularization, stroke and/or myocardial infarction.

The secondary endpoints include:

1. Successful completion of same sitting CABG and coronary stent procedure
2. Successful completion of CABG and PCI during single hospitalization
3. Achievement of complete revascularization
4. Patency of the LIMA and stented vessels as determined by coronary angiography at time of procedures or prior to discharge and by cardiac Computed Tomographic Angiography (CTA) or coronary angiography at 1 year.
5. Stent thrombosis at 24 hours (acute), 30 days (sub acute), and 1 year (late)
6. One-year composite clinical event endpoints of major clinical events including death, repeat revascularization, myocardial infarction, and freedom from angina
7. Comparative analysis of hospital, 30 day, and 1 year events of hybrid CABG patients compared to consecutive patients undergoing off pump CABG with standard thoracotomy during study period

Conditions

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Coronary Artery Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Hybrid CABG/PCI

Patients undergo hybrid, same sitting CABG/PCI as described.

Group Type EXPERIMENTAL

Hybrid CABG/PCI

Intervention Type PROCEDURE

Same sitting hybrid, robotic CABG/PCI

Off-pump CABG

Standard of Care Off Pump CABG

Group Type OTHER

Off Pump CABG

Intervention Type PROCEDURE

Standard of Care Off Pump CABG

Interventions

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Hybrid CABG/PCI

Same sitting hybrid, robotic CABG/PCI

Intervention Type PROCEDURE

Off Pump CABG

Standard of Care Off Pump CABG

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Requirement for CABG
* Anatomy and body habitus suitable for Robotic CABG
* Requirement of revascularization of arteries amendable for PCI but not accessable by Robotic CABG

Exclusion Criteria

* Need for emergent CABG
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pinnacle Health Cardiovascular Institute

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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William Bachinsky, M.D.

Role: PRINCIPAL_INVESTIGATOR

Pinnacle Health Cardiovascular Institute, Inc.

Locations

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UPMC Pinnacle Harrisburg

Harrisburg, Pennsylvania, United States

Site Status

Countries

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United States

Related Links

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http://www.pinnaclehealth.org

Pinnacle Health Cardiovascular Institute

Other Identifiers

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Same Sitting Robotic CABG/PCI

Identifier Type: -

Identifier Source: org_study_id

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