Graft Patency in Beating Heart Vs. Conventional CABG Using Cardiac CT
NCT ID: NCT00259493
Last Updated: 2006-09-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
350 participants
INTERVENTIONAL
2005-12-31
2007-10-31
Brief Summary
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Detailed Description
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The main strategy of CABG is to obtain complete revascularization with the least morbidity and highest long-term patency rates. Current medical literature is conflicted regarding graft patency rates in OPCAB vs. conventional CABG. Data is also limited due to patient refusal for conventional angiography to assess grafts following surgery. Cardiac computed tomography (CT) offers a non-invasive method to assess graft patency that is 100% accurate for the diagnosis of graft patency vs. occlusion. This study is a prospective randomized controlled trial evaluating graft patency in on-pump vs. off-pump CABG using cardiac CT scanning. The study hypothesis is that graft patency rates will be equivalent between the two techniques.
Conditions
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Keywords
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
DOUBLE
Interventions
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Off-Pump Coronary Artery Bypass Graft Surgery
Eligibility Criteria
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Inclusion Criteria
* Patient is hemodynamically stable
* Isolated coronary artery surgery (no valve)
* No contraindications to cardiopulmonary bypass
* No previous surgery (not redo CABG)
Exclusion Criteria
* concomitant cardiac procedures.
* inability to provide written informed consent.
* prior severe reaction to contrast dye :
* life-threatening anaphylactoid reactions
* cardiac dysrhythmias and arrest
* cardiovascular and pulmonary collapse
* elevated serum creatinine (\>150 mmol/L).
* contraindications to cardiopulmonary bypass.
* Age \< 18 years .
18 Years
ALL
No
Sponsors
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Toshiba America Medical Systems, Inc.
INDUSTRY
Trillium Health Centre
OTHER
Principal Investigators
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Tarang N Sheth, MD, FRCPC
Role: PRINCIPAL_INVESTIGATOR
Trillium Health Centre
Gopal Bhatnagar, MD, FRCSC
Role: PRINCIPAL_INVESTIGATOR
Trillium Health Centre
Locations
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Trillium Health Centre
Mississauga, Ontario, Canada
Countries
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Central Contacts
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Other Identifiers
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001
Identifier Type: -
Identifier Source: org_study_id