Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD

NCT ID: NCT00926861

Last Updated: 2010-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

320 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2012-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Choroidal neovascularisation in age related macular degeneration is one of the major causes of legal blindness in the western world existing in two major occurences, the dry and the wet form.The etiology of age related macular degeneration is yet unknown. Genetic factors, oxidative stress, Ischaemia, and aging of the retinal pigment epithelium are discussed as etiologic factors. The risk of rapid vision loss is much higher in wet AMD, a dry form may transform to a wet form. From a prior study the investigators know that the posterior hyaloid is significantly more frequent attached in wet AMD. This study is conducted to examine whether the attached posterior hyaloid is a risk factor to develop wet AMD in dry AMD cases.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Dry Age-related Macular Degeneration Detachment of the Posterior Hyaloid

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Dry AMD

male or female persons aged over 50 years with dry age-related macular degeneration

ultrasound

Intervention Type DEVICE

A-scan and B-scan ultrasound at baseline and month 6,12,24

OCT

Intervention Type DEVICE

Volume scans of spectralis OCT at baseline and month 6,12,24

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

ultrasound

A-scan and B-scan ultrasound at baseline and month 6,12,24

Intervention Type DEVICE

OCT

Volume scans of spectralis OCT at baseline and month 6,12,24

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Dry MD
* Age over 50 years

Exclusion Criteria

* Macular pathologies other than age related macular degeneration (like diabetic maculopathy, macular pucker, macular hole)
* Prior vitrectomy or buckle surgery
* Uveitis posterior, multifocal chorioiditis
* Pathologic myopia
* Diabetic retinopathy
* Visualization of the macula not possible (dens cataract, vitreous haemorrhage)
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Susanne Binder, Prof MD

Role: STUDY_CHAIR

Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery

Vienna, Vienna, Austria

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Austria

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Ilse Krebs, MD

Role: CONTACT

+43171165 ext. 4607

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ilse Krebs, MD

Role: primary

43-17-1165 ext. 94682

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

09-052-0409

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Vitrectomy Retinal Oxygenation
NCT01510691 WITHDRAWN