Prokinetic Drugs and Enteral Nutrition

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Brief Summary

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The purpose of this study is to compare the effect of two drugs that can help in the prevention of regurgitation during the administration of enteral nutrition and define which one is the most effective.

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Detailed Description

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Two prokinetic drugs (metoclopramide and erythromycin) will be compared during the administration of enteral nutrition in critically ill patients. We would like to know which one is the most effective in preventing regurgitation and risk of aspiration, which is a common complication of enteral nutritional support. This will be evaluated by measuring gastric residue every six hours.

Conditions

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Critically Ill Enteral Nutrition

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* critically ill patients
* intubated
* mechanically ventilated
* 18 or older age
* enterally fed

Exclusion Criteria

* prokinetic drugs before start study
* allergy to study medication
* interactions odf study medication with other drugs
* recent gastro-intestinal surgery
* history of esophagectomy or gastrectomy
* suspicion of gastrointestinal perforation
* myasthenia gravis
* liver dysfunction
* less than 7 days in study
* gastro- or jejunostomy

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No