Identification of Gene Biomarkers in Aging Skin

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

121 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-08-31

Study Completion Date

2009-04-30

Brief Summary

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This study is a blinded, prospective, single-center, clinical study conducted in Japanese female subjects between the ages of 20-75 years. This design uses skin biopsy samples from environmentally exposed areas and unexposed (control) areas within the same subjects to assess the gene expression profile from three different age groups.

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Detailed Description

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The primary objective of the skin aging study is to investigate changes in gene expression patterns that occur during the aging process.

Conditions

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Hyperpigmentation Skin Aging

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Young age: 20 to 30 years old

No interventions assigned to this group

Group 2

Middle Age: 38 to 48 years old (pre-menopausal only)

No interventions assigned to this group

Group 3

Elderly Age: 60 to 75 years old (Post-menopausal only)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Individuals who are willing to read and sign an informed consent form prior to participating in the study.
* Individuals who have a temperature of less than or equal to 100 degrees F at the time of biopsy collection.
* Individuals who had not applied any sunless tanning product on the arms within the past year.
* Individuals with no prior history of alcoholism (or who consume fewer than 2 to 3 alcoholic beverages per day).
* Individuals who have not consumed any anti-aging nutritional supplements (multivitamins and multiminerals are acceptable) or aspirin, NSAIDS, or other pain medication in the last 48 hours before biopsy.