Sacral Neuromodulation Test With Bilateral First Stage Tined Lead Procedure in Patients With Non-obstructive Urinary Retention: A Pilot Study

NCT ID: NCT00878176

Last Updated: 2018-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2010-12-31

Brief Summary

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The objective of this study is to determine whether bilateral sacral nerve stimulation with First stage tined lead placement test is more effective than unilateral stimulation, among patients with non obstructive urinary retention.

Detailed Description

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Conditions

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Urinary Retention

Study Design

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Intervention Model

CROSSOVER

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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1

(Crossover study)

Group Type EXPERIMENTAL

First stage tined lead procedure

Intervention Type PROCEDURE

bilateral first stage tined lead placement

Interventions

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First stage tined lead procedure

bilateral first stage tined lead placement

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients who signed the informed consent
* Patients (male and female), aged between 18-70 years, with non obstructive urinary retention.

Two specific subcategories of retention are included

1. Incomplete voiding or incomplete retention (\>100 cc residual) such as hesitancy or intermittency, that are due to an acontractile detrusor or due to urethral sphincter overactivity. The overactivity of the sphincter may occur in absence of detrusor contraction and may be the cause of the lack of detrusor activity.
2. Complete retention. These individuals are completely unable to void.

All patients must have the potential for storing an adequate volume of urine:

i.e., at least 100 ml

Exclusion Criteria

* Known psychiatric disorders
* Current or plans of pregnancy
* Known neurologic diseases or impairment; including DM (severe or uncontrolled diabetes; or diabetes with peripheral nerve involvement), spinal cord injury, MS
* Reiter's syndrome
* Concomitant medical conditions that would limit the success of the procedure such as: active degenerative disc disease, spinal cord injury\< 6 months old, bleeding complications, CVA\< 6 months old etc.
* Extra urethral incontinence
* Pelvic pain of uncertain etiology that is not associated with a voiding dysfunction or where pelvic pain is the primary complaint/ diagnosis.
* Anatomic obstructive voiding disorders
* Current urinary tract infection
* Malignancy of urinary tract
* Severe grade III/ IV pelvic prolapse, cystocele, urethrocele, enterocele
* Proven interstitial cystitis or clinical symptoms of interstitial cystitis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Philip van Kerrebroeck, Professor

Role: PRINCIPAL_INVESTIGATOR

Maastricht University Hospital

Locations

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dept Urology, Maastricht University Hospital

Maastricht, , Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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MEC 09-2-005

Identifier Type: -

Identifier Source: org_study_id

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