Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-09-30

Study Completion Date

2009-03-31

Brief Summary

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The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.

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Detailed Description

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This is a prospective observational study conducted in involutional ptosis patients, which will be submitted to instillation of a single drop of 10% phenylephrine in one eye(Group 1), 2 drops (G2) or 4 drops ( G3).

Video camera will record the images of both eyes before and after drug application at 3, 10, 15 and 30 minutes. The images will be edited to analyze upper and lower lid height.

Conditions

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Blepharoptosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Patients submitted to application of 1 drop of 10% phenylephrine

No interventions assigned to this group

2

Patients submitted to application of 2 drops of 10% phenylephrine

No interventions assigned to this group

3

Patients submitted to application of 4 drops of 10% phenylephrine

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Involutional blepharoptosis
* Upper Margin-reflex distance less or equal 2.0mm
* Good fixation and collaboration

Exclusion Criteria

* Previous eyelid surgeries
* Use of adrenergic or sympathicomimetics drugs
* Myopathies
* Thyroid orbitopathy
* Non-controlled cardiovascular disease

Eligible Sex

ALL

Accepts Healthy Volunteers

No