The Efficacy and Safety of Dexibuprofen Syrup

NCT ID: NCT00812422

Last Updated: 2010-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

260 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2009-05-31

Brief Summary

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The purpose of this study is to compare the safety and efficacy of dexibuprofen syrup and ibuprofen syrup in patients with fever due to common cold.

Detailed Description

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Conditions

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Fever Respiratory Tract Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Dexibuprofen 1

Dexibuprofen 2.5 or 5 mg/kg

Group Type EXPERIMENTAL

Dexibuprofen

Intervention Type DRUG

one dose of Dexibuprofen 2.5 or 5 mg/kg

Dexibuprofen 2

Dexibuprofen 3.5 or 7 mg/kg

Group Type EXPERIMENTAL

Dexibuprofen

Intervention Type DRUG

one dose of Dexibuprofen 3.5 or 7 mg/kg

Ibuprofen

Ibuprofen 5 or 10 mg/kg

Group Type ACTIVE_COMPARATOR

Ibuprofen

Intervention Type DRUG

one dose of Ibuprofen 5 or 10 mg/kg

Interventions

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Dexibuprofen

one dose of Dexibuprofen 2.5 or 5 mg/kg

Intervention Type DRUG

Dexibuprofen

one dose of Dexibuprofen 3.5 or 7 mg/kg

Intervention Type DRUG

Ibuprofen

one dose of Ibuprofen 5 or 10 mg/kg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Common cold with fever
* Age 6 months to 14 years

Exclusion Criteria

* Gastric ulcer
* Bleeding tendency
* Liver disease
* Kidney disease
* Hypertension
* Hypersensitivity to the drug
Minimum Eligible Age

6 Months

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Inje University

OTHER

Sponsor Role lead

Responsible Party

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Inje University Sanggye Paik Hospital

Principal Investigators

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Young Yull Koh

Role: STUDY_DIRECTOR

Seoul National University Hospital

Chang-Keun Kim

Role: PRINCIPAL_INVESTIGATOR

Inje University

Locations

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Asan Medical Center

Seoul, , South Korea

Site Status

Inje University Sanggye Paik Hospital

Seoul, , South Korea

Site Status

Korea University Hospital

Seoul, , South Korea

Site Status

Kyung Hee University Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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AG_DIBU_2007

Identifier Type: -

Identifier Source: org_study_id

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