Acute Sore Throat Pain Study

NCT ID: NCT01535079

Last Updated: 2012-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

186 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2012-11-30

Brief Summary

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"Sore throat is one of the most common complaints encountered in clinical practice. And in 65% of cases, the infection is thought to be viral in nature.

The aim of this study is to evaluate the analgesic profile of 3 Ibuprofen lozenges after single administration in acute sore throat pain."

Detailed Description

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Conditions

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Acute Sore Throat Pain

Keywords

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sore throat pain tonsillopharyngitis upper respiratory tract infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Single administration

V0498TA01A 15 mg

Group Type EXPERIMENTAL

Ibuprofen 15 mg

Intervention Type DRUG

Single administration

V0498TA01A 25 mg

Group Type EXPERIMENTAL

Ibuprofen 25 mg

Intervention Type DRUG

Single administration

V0498TA01A 35 mg

Group Type EXPERIMENTAL

Ibuprofen 35 mg

Intervention Type DRUG

Single administration

Strefen

Positive control

Group Type OTHER

Strefen

Intervention Type DRUG

Single administration

Interventions

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Placebo

Single administration

Intervention Type DRUG

Ibuprofen 35 mg

Single administration

Intervention Type DRUG

Ibuprofen 25 mg

Single administration

Intervention Type DRUG

Ibuprofen 15 mg

Single administration

Intervention Type DRUG

Strefen

Single administration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* male or female patients 18 years and older
* patients with a sore throat associated or not with an Upper Respiratory Tract Infection ≥ 24 hours and ≤ 5 days duration, in the absence of Streptococcus group A

Exclusion Criteria

* patients with hypersensitivity to Ibuprofen or other NSAIDs or the excipients.
* patients having used analgesics or antiseptics or any topical throat treatment or any local medication containing a local oral anaesthetic within 6 hours before study entry and who use analgesics more than ≥ 3 times per week.
* patients having used any anti inflammatory treatment or any long-acting or slow release analgesics within 12 hours before study entry
* patients having taken antibiotics within 14 days before study entry.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pierre Fabre Medicament

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Eurofins Optimed

Gières, , France

Site Status

Eurofins Optimed Lyon

Pierre-Bénite, , France

Site Status

Erfurt, , Germany

Site Status

Cardiff, , United Kingdom

Site Status

Countries

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France Germany United Kingdom

Other Identifiers

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2011-005848-10

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

V00498 TA 2 01

Identifier Type: -

Identifier Source: org_study_id