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Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD

NCT ID: NCT00790634

Last Updated: 2008-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-12-31

Study Completion Date

2011-12-31

Brief Summary

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The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.

Detailed Description

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Conditions

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Parkinson's Disease Obsessive-Compulsive Disorder

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Parkinson's Disease

Patients with idiopathic Parkinson's disease

No interventions assigned to this group

Obsessive-compulsive disorder

Individuals with a diagnosis of obsessive-compulsive disorder

No interventions assigned to this group

OCD controls

Healthy controls, matched in age and number to obsessive-compulsive group

No interventions assigned to this group

PD controls

Healthy controls, matched in age and number to Parkinson's disease group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* idiopathic PD or
* OCD
* for control group - age-matched to study groups

Exclusion Criteria

* psychotic symptoms (past or present)
* head injury with loss of consciousness
* other neurological conditions (excepting PD in PD group)
* for OCD group - use of dopaminergic medications
Minimum Eligible Age

16 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Haifa

OTHER

Sponsor Role collaborator

Israel Science Foundation

OTHER

Sponsor Role collaborator

Sheba Medical Center

OTHER_GOV

Sponsor Role lead

Responsible Party

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Sheba Medical Center

Central Contacts

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Sharon Hassin, MD

Role: CONTACT

Phone: 97235305791

Email: [email protected]

Sari Meril, M.Sc

Role: CONTACT

Phone: 972

Other Identifiers

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SHEBA-08-5473-SH-CTIL

Identifier Type: -

Identifier Source: org_study_id