Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity

NCT ID: NCT00775970

Last Updated: 2008-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Brief Summary

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The purpose of this study is to determine whether walking exercise after dietary treatment of obesity is associated with a decrease of the daily spontaneous physical activity and\\or with an increase of the time spent in sedentary activities. Our hypothesis is that the practice of walking as an exercise during the phase of weight stability following the dietary treatment of obesity leads to a reduction of spontaneous physical activity and\\or to an increase in the time spent in sedentary activities.

Detailed Description

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The subjects of this study will be randomised in 2 groups:

A group with usual follow-up and a group with usual follow-up associated with recommendations to introduce a program of walking achieving gradually 2000-2500 kcal/week.

Conditions

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Obesity

Keywords

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Obesity Weight loss maintenance Spontaneous physical activity Lipid oxydation Walking

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Interventions

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walking activity

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Women from 18 to 50 year-old
* In phase of weight stability
* BMI\<40kg/m²

Exclusion Criteria

* History of bariatric surgery
* Diabetes
* Suspicion of obstructive sleep apnea syndrome
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Tours

OTHER

Sponsor Role lead

Responsible Party

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University Hospital, Tours

Principal Investigators

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David JACOBI, MD

Role: PRINCIPAL_INVESTIGATOR

Service de médecine Interne-Nutrition

Locations

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Service de Médecine Interne - Nutrition / CHRU de Tours

Tours, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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David JACOBI, MD

Role: CONTACT

Phone: +33247474727

Email: [email protected]

Pascaline RAMEAU, CRA

Role: CONTACT

Phone: +33247366249

Email: [email protected]

Facility Contacts

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David JACOBI, MD

Role: primary

References

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Brage S, Brage N, Franks PW, Ekelund U, Wong MY, Andersen LB, Froberg K, Wareham NJ. Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure. J Appl Physiol (1985). 2004 Jan;96(1):343-51. doi: 10.1152/japplphysiol.00703.2003. Epub 2003 Sep 12.

Reference Type BACKGROUND
PMID: 12972441 (View on PubMed)

Fogelholm M, Kukkonen-Harjula K. Does physical activity prevent weight gain--a systematic review. Obes Rev. 2000 Oct;1(2):95-111. doi: 10.1046/j.1467-789x.2000.00016.x.

Reference Type BACKGROUND
PMID: 12119991 (View on PubMed)

Froidevaux F, Schutz Y, Christin L, Jequier E. Energy expenditure in obese women before and during weight loss, after refeeding, and in the weight-relapse period. Am J Clin Nutr. 1993 Jan;57(1):35-42. doi: 10.1093/ajcn/57.1.35.

Reference Type BACKGROUND
PMID: 8416662 (View on PubMed)

Jequier E, Schutz Y. Long-term measurements of energy expenditure in humans using a respiration chamber. Am J Clin Nutr. 1983 Dec;38(6):989-98. doi: 10.1093/ajcn/38.6.989.

Reference Type BACKGROUND
PMID: 6650455 (View on PubMed)

Kraemer WJ, Volek JS, Clark KL, Gordon SE, Incledon T, Puhl SM, Triplett-McBride NT, McBride JM, Putukian M, Sebastianelli WJ. Physiological adaptations to a weight-loss dietary regimen and exercise programs in women. J Appl Physiol (1985). 1997 Jul;83(1):270-9. doi: 10.1152/jappl.1997.83.1.270.

Reference Type BACKGROUND
PMID: 9216973 (View on PubMed)

Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science. 1999 Jan 8;283(5399):212-4. doi: 10.1126/science.283.5399.212.

Reference Type BACKGROUND
PMID: 9880251 (View on PubMed)

Levine JA, Schleusner SJ, Jensen MD. Energy expenditure of nonexercise activity. Am J Clin Nutr. 2000 Dec;72(6):1451-4. doi: 10.1093/ajcn/72.6.1451.

Reference Type BACKGROUND
PMID: 11101470 (View on PubMed)

Nicklas BJ, Rogus EM, Goldberg AP. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol. 1997 Jul;273(1 Pt 1):E149-55. doi: 10.1152/ajpendo.1997.273.1.E149.

Reference Type BACKGROUND
PMID: 9252491 (View on PubMed)

van Aggel-Leijssen DP, Saris WH, Hul GB, van Baak MA. Short-term effects of weight loss with or without low-intensity exercise training on fat metabolism in obese men. Am J Clin Nutr. 2001 Mar;73(3):523-31. doi: 10.1093/ajcn/73.3.523.

Reference Type BACKGROUND
PMID: 11237927 (View on PubMed)

van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Hul GB, van Baak MA. The effect of low-intensity exercise training on fat metabolism of obese women. Obes Res. 2001 Feb;9(2):86-96. doi: 10.1038/oby.2001.11.

Reference Type BACKGROUND
PMID: 11316351 (View on PubMed)

Zurlo F, Lillioja S, Esposito-Del Puente A, Nyomba BL, Raz I, Saad MF, Swinburn BA, Knowler WC, Bogardus C, Ravussin E. Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physiol. 1990 Nov;259(5 Pt 1):E650-7. doi: 10.1152/ajpendo.1990.259.5.E650.

Reference Type BACKGROUND
PMID: 2240203 (View on PubMed)

Other Identifiers

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PHRI07-DJ APS

Identifier Type: -

Identifier Source: org_study_id