Physical Activity and Food Intake Interaction: Effect of Weight Loss in Obese Adolescent

NCT ID: NCT02664844

Last Updated: 2016-01-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2013-09-30
• Study Completion Date: 2015-12-31

Brief Summary

In obese adolescents, energy expenditure (EE) of chronic high intensity muscular exercise (> 70% VO2max) conducted one hour before a meal causes an anorectic effect at lunch and dinner the same day. The effect on food intake of the distribution of this exercise into two sessions during 24h remains to be determined. In addition, a multidisciplinary load of obesity generates a loss of body weight in the short term, which we do not know the effects on energy balance. To our knowledge, the impact of weight loss on the anorectic effect of muscle exercise is unknown.

Detailed Description

Two measuring sequences will be carried out before (M0) and after 4 months (M4) of a multidisciplinary treatment program of four months. Each sequence will have three days: a "sedentary" day (SED) and two days "exercise" (EX). During the exercise day "EX1", a continuous intense exercise will be conducted for 40 min at 70% VO2max of subjects. During the second day exercise "EX2" teenage realize two exercise representing the same DE as EX1 in the morning (50% ED) and late afternoon (50% ED). The multidisciplinary management program (without energy restriction) controlled by institution consists of nutrition education, physical activity and therapeutic education. The exercise program will involve the activity sessions controlled and supervised by a sports educator and interactive sessions using a scientifically validated physical activity program (Biomouv®).

Conditions

Obesity

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Obese adolescent

Group Type: EXPERIMENTAL

Physical activity

Intervention Type: BEHAVIORAL

Interventions

Physical activity

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Overweight adolescents (over the 90 th percentile of the international cut-off point)
• Sedentary (according to the IPAQ-A questionnaire)
• Without eating disorders (according to the DEBQ questionnaire)

Exclusion Criteria

• Medical or surgical antecedents that are incompatible with the study: cardiovascular, endocrine or digestive disease.
• Drugs that could interfere with the results of the study
• Surgical intervention in the 3 months
• Regular consumption of tobacco or Alcohol
• patients on a diet with caloric restriction
• Refusal to sign the consent form
• Regular practice of sport and intensive

• Minimum Eligible Age: 12 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Clermont-Ferrand

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

CHU Clermont-Ferrand

Clermont-Ferrand, , France

Countries

France

Other Identifiers

CHU-0255

Identifier Type: -

Identifier Source: org_study_id