Peripheral Metabolic Effects of Ghrelin

NCT ID: NCT00771940

Last Updated: 2009-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-10-31

Study Completion Date

2009-01-31

Brief Summary

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The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.

Detailed Description

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Conditions

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Healthy Controls

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Ghrelin

Group Type ACTIVE_COMPARATOR

Ghrelin

Intervention Type DRUG

Solvent, cont. infusion

Interventions

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Ghrelin

Solvent, cont. infusion

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. BMI \< 27 kg/m2
2. Written informed consent
3. Non-smoker

Exclusion Criteria

1. Any disease including epilepsy
2. Any use of medications (excl. paracetamol)
3. Present or previous malignancy
4. Alcohol dependency
5. Allergy to any trial medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Aarhus University Hospital

Principal Investigators

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Jens Otto L. Jorgensen, MD

Role: STUDY_DIRECTOR

Medical Department M, Aarhus University Horpital, Denmark

Esben T Vestergaard, PhD

Role: PRINCIPAL_INVESTIGATOR

Medical Department M, Aarhus University Hospital, Denmark

Locations

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Aarhus University Hospital

Aarhus, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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M-2007008

Identifier Type: -

Identifier Source: org_study_id

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