Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
1331 participants
OBSERVATIONAL
2010-02-28
2015-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Standard of Care
Biomarker (not used as an intervention)
This study is an observational study. There is no intervention.
Interventions
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Biomarker (not used as an intervention)
This study is an observational study. There is no intervention.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* All patients are required to be at least 21 years of age and be able to understand and sign the informed consent form
* Patient must be a current or former cigarette smoker
Exclusion Criteria
* Inability to understand the written consent form and comply with requirements of the study
* History of prior primary lung cancer
* Immediately prior to bronchoscopy, the patient has been on a mechanical ventilator for \>24 consecutive hours.
21 Years
ALL
No
Sponsors
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University of Pennsylvania
OTHER
Columbia University
OTHER
Temple University
OTHER
Indiana University
OTHER
University of Alabama at Birmingham
OTHER
University of Missouri-Columbia
OTHER
Louisiana State University Health Sciences Center in New Orleans
OTHER
University of Wisconsin, Madison
OTHER
Medical University of South Carolina
OTHER
National Jewish Health
OTHER
Overlake Hospital Bellevue WA
UNKNOWN
Pulmonary and Allergy Associates of New Jersey
UNKNOWN
Pulmonary Associates of Arizona
UNKNOWN
William Jennings Bryan Dorn VA Medical Center
FED
Virginia Commonwealth University
OTHER
Jamaica Hospital Medical Center
OTHER
North Florida/South Georgia Veterans Health System
OTHER
Steward St. Elizabeth's Medical Center of Boston, Inc.
OTHER
University of California, Davis
OTHER
Yale University
OTHER
The Cleveland Clinic
OTHER
Allegro Diagnostics, Corp.
INDUSTRY
Responsible Party
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Principal Investigators
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Duncan Whitney, PhD
Role: STUDY_DIRECTOR
Allegro Diagnostics
Locations
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University of Alabama
Birmingham, Alabama, United States
Pulmonary Associates of Arizona
Phoenix, Arizona, United States
University of California- Davis
Sacramento, California, United States
National Jewish Health
Denver, Colorado, United States
Yale Univeristy
New Haven, Connecticut, United States
North Florida/South Georgia VA
Gainesville, Florida, United States
Indiana University
Indianapolis, Indiana, United States
LSU
New Orleans, Louisiana, United States
St. Elizabeth's Medical Center
Boston, Massachusetts, United States
University of Missouri
Columbia, Missouri, United States
Pulmonary and Allergy Associates of New Jersey
Summit, New Jersey, United States
Jamaica Hospital Medical Center
Jamaica, New York, United States
Columbia University
New York, New York, United States
Cleveland Clinic
Cleveland, Ohio, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Temple University
Philadelphia, Pennsylvania, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Dorn VA
Columbia, South Carolina, United States
Virginia Commonwealth University
Richmond, Virginia, United States
Overlake Hospital
Bellevue, Washington, United States
University of Wisconsin
Madison, Wisconsin, United States
Countries
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References
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Vachani A, Whitney DH, Parsons EC, Lenburg M, Ferguson JS, Silvestri GA, Spira A. Clinical Utility of a Bronchial Genomic Classifier in Patients With Suspected Lung Cancer. Chest. 2016 Jul;150(1):210-8. doi: 10.1016/j.chest.2016.02.636. Epub 2016 Feb 16.
Silvestri GA, Vachani A, Whitney D, Elashoff M, Porta Smith K, Ferguson JS, Parsons E, Mitra N, Brody J, Lenburg ME, Spira A; AEGIS Study Team. A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer. N Engl J Med. 2015 Jul 16;373(3):243-51. doi: 10.1056/NEJMoa1504601. Epub 2015 May 17.
Other Identifiers
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ADx-0001: IDE G090194
Identifier Type: -
Identifier Source: org_study_id
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