Sunscreen: Persistence of Sun Protection Factor and the Influence on Vitamin D

NCT ID: NCT00711256

Last Updated: 2008-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-07-31

Study Completion Date

2008-11-30

Brief Summary

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The investigators want to investigate whether sunscreen is removed by clothing and to what extend when the amount of sunscreen applied varies.Does clothing reduce the SPF when clothes are put on 20, 8, or 4 minutes after sunscreen application? The investigators also want to investigate the persistence of sunscreen during eight hours indoor. How much does the SPF reduces? Furthermore, we want to investigate whether sunscreen in the layers 2, 1, and 0.5 mg/cm2 reduce the vitamin D production in the skin.

Detailed Description

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Conditions

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Vitamin D Production in the Skin Sunscreen Persistence

Keywords

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Sunscreen Application Vitamin D Sun protection factor Clothing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

No sunscreen applied

Group Type ACTIVE_COMPARATOR

UVB light

Intervention Type RADIATION

duration 4 times 1 minute radiation on the trunk.

2

Sunscreen applied 0.5 mg/cm2

Group Type ACTIVE_COMPARATOR

UVB light

Intervention Type RADIATION

duration 4 times 1 minute radiation on the trunk.

3

Sunscreen applied 1mg/cm2

Group Type ACTIVE_COMPARATOR

UVB light

Intervention Type RADIATION

duration 4 times 1 minute radiation on the trunk.

4

Sunscreen applied 2mg/cm2

Group Type ACTIVE_COMPARATOR

sunscreen MATAS sunlotion SPF 8

Intervention Type OTHER

UVB light

Intervention Type RADIATION

duration 4 times 1 minute radiation on the trunk.

Interventions

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sunscreen MATAS sunlotion SPF 8

Intervention Type OTHER

UVB light

duration 4 times 1 minute radiation on the trunk.

Intervention Type RADIATION

Other Intervention Names

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MATAS sollotion. Matas Denmark, 3400 Alleroed

Eligibility Criteria

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Inclusion Criteria

* Healthy participants.
* \> 18 years.
* Skin type I, II, and III.

Exclusion Criteria

* Pregnancy.
* Medicin use.
* Skin or other diseases.
* The participants must not have been in solarium or gotten sun on their trunks in the 3 months before the study start and during the study.
* Skin types IV and above.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Bispebjerg Hospital

OTHER

Sponsor Role lead

Responsible Party

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Bispebjerg Hospital

Locations

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Bispebjerg Hospital

Copenhagen, KBH NV, Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Hans Christian Wulf, Dr.med

Role: CONTACT

Phone: +45 3135 3155

Ditte Beyer, stud.med

Role: CONTACT

Phone: +45 2014 1423

Email: [email protected]

Facility Contacts

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HC Wulf, Dr.med

Role: primary

Ditte Beyer, stud.med

Role: backup

References

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Beyer DM, Faurschou A, Philipsen PA, Haedersdal M, Wulf HC. Sun protection factor persistence on human skin during a day without physical activity or ultraviolet exposure. Photodermatol Photoimmunol Photomed. 2010 Feb;26(1):22-7. doi: 10.1111/j.1600-0781.2009.00479.x.

Reference Type DERIVED
PMID: 20070835 (View on PubMed)

Other Identifiers

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H-B-2007-120

Identifier Type: -

Identifier Source: org_study_id