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UVB Light and Sunscreen

NCT ID: NCT00818467

Last Updated: 2009-12-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-05-31

Study Completion Date

2009-02-28

Brief Summary

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Patients need vitamin D which is normally produced in the skin in response to ultraviolet light from the sun. Vitamin D is important for calcium absorption and good bone health. Physicians have been using sunscreens to protect patients from skin cancer and the aging effects of sunlight for a least a half a century. Dermatologists have promoted sunscreen use to restrict sunlight exposure especially in white Caucasians. If this behavior is done 100% of the time when outdoors individuals may suffer from vitamin D deficiency. It is impossible to influence persons' behavior to wear sunscreens all the time when outdoors. With the use of sunless tanning agent (DHA), once a week, we can obtain a continuous sunscreen in the top layer of the skin that will not wash off, can't be removed with soap and water, or removed by perspiration. Under these circumstances we can answer the scientific question, will sunscreen use inhibit the production of vitamin D in the skin?

Detailed Description

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Conditions

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Vitamin D Status

Keywords

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Skin tone Vitamin D

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Tanning spray

To characterize the 25(OH)D response to 4 weeks of thrice weekly 40 mJ of UV-B light in a group of normal subjects with skin types I and II while using multiple applications of 3% DHA for five weeks.

Group Type EXPERIMENTAL

Tanning spray

Intervention Type OTHER

using 3% DHA twice a week for the 1st week and then once a week for 4 weeks and receiving 40mJ UV-B phototherapy three times a week for four weeks

UVB

To characterize the 25(OH)D response to 4 weeks of thrice weekly 40 mJ of UV-B light in a control group of normal subjects with skin types I and II who are not using 3% DHA applications.

Group Type ACTIVE_COMPARATOR

UVB

Intervention Type OTHER

receiving 40mJ UV-B phototherapy three times a week for four weeks

Interventions

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Tanning spray

using 3% DHA twice a week for the 1st week and then once a week for 4 weeks and receiving 40mJ UV-B phototherapy three times a week for four weeks

Intervention Type OTHER

UVB

receiving 40mJ UV-B phototherapy three times a week for four weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* males or females
* ages 19-50 with less than 16 oz milk per day
* less than 10 hours of sun per week
* no Vitamin D supplements
* no anticonvulsants
* no barbiturates
* no steroids
* no meds that increase photosensitivity
* no granulomatous disease
* no liver or kidney disease
* no history of skin cancer
* BMI less than 30
* skin types I \& II

Exclusion Criteria

* None
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The UV Foundation

OTHER

Sponsor Role collaborator

Creighton University

OTHER

Sponsor Role lead

Responsible Party

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Creighton University

Principal Investigators

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Laura A Armas, MD

Role: PRINCIPAL_INVESTIGATOR

Creighton University

Locations

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Creighton University

Omaha, Nebraska, United States

Site Status

Countries

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United States

Other Identifiers

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Creighton 7

Identifier Type: -

Identifier Source: org_study_id