Comparison of Sunlight Exposure and Vitamin D Supplementation on Serum 25-hydroxyvitamin D Levels

NCT ID: NCT03310242

Last Updated: 2017-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-01

Study Completion Date

2015-11-30

Brief Summary

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This study aimed to compare the effects between sunlight exposure and oral vitamin D supplementation on serum 25-hydroxyvitamin D concentration and metabolic markers in Korean young adults.

Detailed Description

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Conditions

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Vitamin D Deficiency Cardiometabolic Risk Factors

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Sunlight Exposure

Everyday sunlight exposure around noon for 20-30 minutes for 8 weeks

Group Type EXPERIMENTAL

Sunlight Exposure

Intervention Type BEHAVIORAL

* Everyday sunlight exposure around noon for 20-30 minutes for 8 weeks
* Completing a Sun Diary after sunlight exposure

Vitamin D Supplementation

Supplementation of vitamin D3 500 IU/day for 8 weeks

Group Type EXPERIMENTAL

Vitamin D Supplementation

Intervention Type DIETARY_SUPPLEMENT

\- Supplementation of vitamin D3 500 IU/day for 8 weeks

Placebo

Intake of placebo for 8 weeks

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

\- Intake of placebo for 8 weeks

Interventions

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Sunlight Exposure

* Everyday sunlight exposure around noon for 20-30 minutes for 8 weeks
* Completing a Sun Diary after sunlight exposure

Intervention Type BEHAVIORAL

Vitamin D Supplementation

\- Supplementation of vitamin D3 500 IU/day for 8 weeks

Intervention Type DIETARY_SUPPLEMENT

Placebo

\- Intake of placebo for 8 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Serum 25(OH)vitamin D \< 12ng/mL
* age between 18 and 39 years
* Korean men and women

Exclusion Criteria

* Vitamin D supplementation within 2 months
* Photosensitivity or UV allergy
* History of hyperparathyroidism/hypercalciuria/kidney stone/skin cancer and other cancer
* Under medication for hypertension, dyslipidemia, and diabetes
* Intake of photosensitive medicine during study period
* Exposure of strong UV (e.g., beach, sun tanning) during study period
* Pregnant/breast-feeding women
Minimum Eligible Age

18 Years

Maximum Eligible Age

39 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hee-Kyung Joh, PhD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University College of Medicine/Seoul National University Hospital

References

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Joh HK, Hwang SS, Cho B, Lim CS, Jung SE. Effect of sun exposure versus oral vitamin D supplementation on serum 25-hydroxyvitamin D concentrations in young adults: A randomized clinical trial. Clin Nutr. 2020 Mar;39(3):727-736. doi: 10.1016/j.clnu.2019.03.021. Epub 2019 Mar 21.

Reference Type DERIVED
PMID: 30987813 (View on PubMed)

Other Identifiers

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H-1504-112-668

Identifier Type: -

Identifier Source: org_study_id