Metabolic Derangements in Acute Heart Failure Syndrome

NCT ID: NCT00682175

Last Updated: 2009-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-05-31

Study Completion Date

2009-03-31

Brief Summary

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To determine the association of both neurohormonal and hemodynamic alterations associated with metabolic abnormalities in acute heart failure syndrome.

Detailed Description

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Conditions

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Congestive Heart Failure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Observation

Adult (age \> 18 yrs) patients admitted to the Heart Failure Intensive Care Unit with Acute Heart Failure Syndrome requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.

Observational

Intervention Type OTHER

Pulmonary Artery pressure (PA), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), and cardiac index (CI). This data will be collected after 24 ± 2 and 48 ± 2 hours of standard heart failure therapy

Interventions

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Observational

Pulmonary Artery pressure (PA), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), and cardiac index (CI). This data will be collected after 24 ± 2 and 48 ± 2 hours of standard heart failure therapy

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult (age \> 18 yrs) patients admitted to the Heart Failure Intensive Care Unit (H22) with Acute Heart Failure Syndrome (AHFS) requiring placement of a Pulmonary Artery catheter for hemodynamically guided therapy.

Exclusion Criteria

* History of Congenital Heart Disease.
* Acute HF in the setting of acute myocardial infarction.
* Severe Anemia
* Patients listed for cardiac transplantation.
* Terminal Malignancy, AIDS or CNS disease.
* Concomitant sepsis, ARDS, trauma, aortic dissection, or pericardial tamponade
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Cleveland Clinic

OTHER

Sponsor Role lead

Responsible Party

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Cleveland Clinic Foundation

Principal Investigators

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George Sokos, MD

Role: PRINCIPAL_INVESTIGATOR

The Cleveland Clinic

Other Identifiers

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08-169

Identifier Type: -

Identifier Source: org_study_id

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