Comparison of Two Type of Laryngeal Mask : I-Gel & LMA ProSeal

NCT ID: NCT00624403

Last Updated: 2015-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

700 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-03-31

Study Completion Date

2013-12-31

Brief Summary

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The i-gel is a new supra glottic airway device with a non inflatable cuff and an oesophageal vent. The aim of this study is to compare this device to the LMA ProSeal. The study is approved by the institutional ethic committee. 222 patients will be enrolled in each group. The objectives of the study will be to compare insertion success rate, leak pressure, ventilatory parameters and adverse event rate.

Detailed Description

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Supraglottic airway devices are now widely used for surgery requiring general anesthesia. Airway devices are safe and their morbidity rate is very low. The i-gel (Intersurgical Ltd, Wokingham, Berkshire, UK) is a new single-use non-inflatable supraglottic airway device that has not been evaluated in a comparative study.

The aim of this study is to compare i-gel with the LMA ProSeal in a randomized study. Anesthesia protocol is standardized. The supraglottic devices are compared in term of insertion success rate, leak pressure, ventilatory parameters and adverse events. The aim is to demonstrate an enhancement in term of insertion success rate and a diminution of the adverse events. Statistical analysis will used percentage, confidence interval and chi 2 or Fischer's exact test for qualitative data. Quantitative data will be analyzed in mean, standard deviation. Comparison will be made with a student t test or a wilcoxon test. P \< 0,05 is statistically significant.

Conditions

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Endotracheal Intubation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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1

LMA ProSeal

Group Type ACTIVE_COMPARATOR

Laryngeal mask insertion (LMA ProSeal)

Intervention Type DEVICE

Laryngeal mask insertion

2

I-Gel

Group Type EXPERIMENTAL

Laryngeal mask insertion (I-Gel)

Intervention Type DEVICE

Laryngeal mask insertion

Interventions

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Laryngeal mask insertion (LMA ProSeal)

Laryngeal mask insertion

Intervention Type DEVICE

Laryngeal mask insertion (I-Gel)

Laryngeal mask insertion

Intervention Type DEVICE

Other Intervention Names

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LMA ProSeal I-Gel

Eligibility Criteria

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Inclusion Criteria

* Weight \> 30 kg
* Surgery allowing the use of laryngeal mask as airway management
* Written informed consent

Exclusion Criteria

* Difficult intubation criteria (defined by French Anesthesia-Reanimation Society)
* Pulmonary disease
* Gastroesophageal reflux antecedent
* Coeliosurgery
* Inhalation risk
* Hiatus hernia
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Bordeaux

OTHER

Sponsor Role lead

Responsible Party

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University Hospital, Bordeaux

Principal Investigators

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Anne-Marie CROS, Dr

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Bordeaux

Locations

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Uniersity Hospital, Bordeaux

Bordeaux, , France

Site Status

Countries

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France

References

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Cros AM. [New laryngeal mask airway: easy and evolution to an better safety]. Ann Fr Anesth Reanim. 2006 Aug;25(8):804-5. doi: 10.1016/j.annfar.2006.06.009. Epub 2006 Jul 20. No abstract available. French.

Reference Type BACKGROUND
PMID: 16859880 (View on PubMed)

Asai T. Editorial II: Who is at increased risk of pulmonary aspiration? Br J Anaesth. 2004 Oct;93(4):497-500. doi: 10.1093/bja/aeh234. No abstract available.

Reference Type BACKGROUND
PMID: 15361474 (View on PubMed)

Cook TM, Lee G, Nolan JP. The ProSeal laryngeal mask airway: a review of the literature. Can J Anaesth. 2005 Aug-Sep;52(7):739-60. doi: 10.1007/BF03016565.

Reference Type BACKGROUND
PMID: 16103390 (View on PubMed)

Keller C, Brimacombe J, Kleinsasser A, Loeckinger A. Does the ProSeal laryngeal mask airway prevent aspiration of regurgitated fluid? Anesth Analg. 2000 Oct;91(4):1017-20. doi: 10.1097/00000539-200010000-00046.

Reference Type BACKGROUND
PMID: 11004067 (View on PubMed)

Brimacombe J, Richardson C, Keller C, Donald S. Mechanical closure of the vocal cords with the laryngeal mask airway ProSeal. Br J Anaesth. 2002 Feb;88(2):296-7. doi: 10.1093/bja/88.2.296.

Reference Type BACKGROUND
PMID: 11878665 (View on PubMed)

Levitan RM, Kinkle WC. Initial anatomic investigations of the I-gel airway: a novel supraglottic airway without inflatable cuff. Anaesthesia. 2005 Oct;60(10):1022-6. doi: 10.1111/j.1365-2044.2005.04258.x.

Reference Type BACKGROUND
PMID: 16179048 (View on PubMed)

Cook TM, McKinstry C, Hardy R, Twigg S. Randomized crossover comparison of the ProSeal laryngeal mask airway with the Laryngeal Tube during anaesthesia with controlled ventilation. Br J Anaesth. 2003 Nov;91(5):678-83. doi: 10.1093/bja/aeg239.

Reference Type BACKGROUND
PMID: 14570790 (View on PubMed)

Cook TM, Nolan JP, Verghese C, Strube PJ, Lees M, Millar JM, Baskett PJ. Randomized crossover comparison of the proseal with the classic laryngeal mask airway in unparalysed anaesthetized patients. Br J Anaesth. 2002 Apr;88(4):527-33. doi: 10.1093/bja/88.4.527.

Reference Type BACKGROUND
PMID: 12066729 (View on PubMed)

Other Identifiers

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CHUBX 2007/22

Identifier Type: -

Identifier Source: org_study_id

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