Use of Atropine in Tredmill Stress Testing

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-12-31

Study Completion Date

2009-10-31

Brief Summary

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The aim of this study is to evaluate the Safety and feasibility of atropine added during treadmill stress testing in patients with chronotropic incompetence or poor exercise capacity.

Our hypothesis is that we can increase heart rate by using atropin in these patients, so we will achieve more conclusive results.

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Detailed Description

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Conditions

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Chest Pain

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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1

Pateints who achieve target haert rate or conclusive test will not be given Atropine

Group Type PLACEBO_COMPARATOR

Atropine

Intervention Type DRUG

I.V Atropine 0.5mg up to 2 mg

2

Patients who won't achieve tarhet heart rate or conclusive results will be given Atropine

Group Type ACTIVE_COMPARATOR

Atropine

Intervention Type DRUG

I.V Atropine 0.5mg up to 2 mg

Interventions

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Atropine

I.V Atropine 0.5mg up to 2 mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with chest pain without evidence of ischemia eligible for exercise test.
* Age\> 18 years old

Exclusion Criteria

Absolute:

* Patients with LBBB
* Unstable Angina
* Recent Myocardial Infarction
* Un controlled Arrythmia
* Congestive heart faliure
* Severe symptomatic valvular heart disease
* Acute Pulmonary Embolism
* Acute perimyocarditis
* Acute aortic dissection

Relative:

* Lt main stenosis
* Severe hypertention (Systolic\> 200 mmHg; Diastolic \> 100 mmHg)
* Cardiomyopathy
* Obstructiove abnormalities
* Psychiatric disorders
* High degree AV Block

Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No