Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
PHASE4
60 participants
INTERVENTIONAL
2002-11-30
2008-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
placebo
placebo
atenolol
atenolol
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
atenolol
placebo
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* ability to give informed consent
* ability to tolerate beta-blocker therapy
* ability to comply with follow-up requirements
Exclusion Criteria
* EKG documented 2nd or 3rd degree heart block
* EKG documented sinus bradycardia
* Serum creatinine \> 2.0
* current treatment asthma
* history of rheumatoid arthritis
* history of Crohn's disease
* history of lupus
* history of inflammatory cancer
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Medtronic - MITG
INDUSTRY
Saini Foundation
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Cape Cod Hospital
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Vikas Saini, M.D.
Role: PRINCIPAL_INVESTIGATOR
Dept Medicine, Cape Cod Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Cape Cod Hospital
Hyannis, Massachusetts, United States
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
PEACK
Identifier Type: -
Identifier Source: org_study_id