Optical Biopsy of Human Skin in Conjunction With Laser Treatment

NCT ID: NCT00540566

Last Updated: 2022-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

113 participants

Study Classification

OBSERVATIONAL

Study Start Date

1999-06-30

Study Completion Date

2008-07-31

Brief Summary

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This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

Detailed Description

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The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.

Conditions

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Malignant Melanoma Merkel Cell Carcinoma Basal Cell Carcinoma Squamous Cell Carcinoma Atypical Nevi Congenital Nevi Seborrheic Keratosis Paget's Disease Dermatofibroma Kaposi's Sarcoma Port Wine Stain Hemangioma Tattoos Scleroderma Burns

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Optical Biopsy

Optical Biopsy imaging

Optical Biopsy imaging

Intervention Type DEVICE

Optical Biopsy imaging

Interventions

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Optical Biopsy imaging

Optical Biopsy imaging

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female age \> 18 years

Exclusion Criteria

* current participation in any other investigational drug evaluation
* inability to understand and carry out instructions
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beckman Laser Institute University of California Irvine

OTHER

Sponsor Role collaborator

University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Beckman Laser Institute and Medical Center

J.S.Nelson, MD,PhD,Professor of Surgery and Biomedical Engineering

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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John S Nelson, M.D,Ph.D

Role: PRINCIPAL_INVESTIGATOR

Beckman Laser Institue, University of California Irvine

Locations

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Beckman Laser Institute, Unversity of California Irvine

Irvine, California, United States

Site Status

Countries

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United States

Other Identifiers

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1996200

Identifier Type: -

Identifier Source: org_study_id

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