Transcriptomic Analysis and Optical Coherence Tomography Combined for Patients With Basal Cell Carcinoma

NCT ID: NCT06813833

Last Updated: 2025-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-06

Study Completion Date

2025-05-31

Brief Summary

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The goal of this observational study is to learn if tape strip for transcriptomic (RNA) analysis and optical coherence tomography (OCT) combined can optimize noninvasive management of basal cell carcinoma (BCC) patients.

The main question of the study is to examine if the combination of these two techniques, transcriptomic and OCT, can improve noninvasive detection of human BCCs.

All included patients will undergo 1) an OCT scan and 2) a tape strip collection for transcriptomic analysis from the same BCC.

Detailed Description

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Conditions

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Basal Cell Carcinomas

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients \> 18 years with clinical suspicious BCC for inclusion in the study and BCC histopathology diagnosis for inclusion in our analysis.

Exclusion Criteria

* Patients with a BCC in areas not amenable to OCT (e.g., around the eye).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

Bispebjerg Hospital

OTHER

Sponsor Role lead

Responsible Party

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Merete Haedersdal

Professor, Chief Physician, DMSc, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Merete Haedersdal, Professor, MD, DMSc, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Dermatology, Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark

Locations

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Department of Dermatology, Bispebjerg Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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H-24060543

Identifier Type: OTHER

Identifier Source: secondary_id

H-24060543

Identifier Type: -

Identifier Source: org_study_id

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