The Influence of Personality on Pulmonary Fibrosis and Sarcoidosis

NCT ID: NCT00504621

Last Updated: 2014-03-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 450 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2007-08-31
• Study Completion Date: 2009-01-31

Brief Summary

A number of studies have shown that the quality of life of two common interstitial lung diseases (ild), sarcoidosis and pulmonary fibrosis patients, is impaired and that fatigue is a substantial problem for those patients. Furthermore, breathlessness is an additional major problem in pulmonary fibrosis. In the field of cardiovascular disease and breast cancer, personality factors have shown to play a role in patient's morbidity, mortality, quality of life, fatigue, depressive symptoms, and one study showed a predictive role of personality factors in health care consumption. No studies examining personality factors have been performed in sarcoidosis or pulmonary fibrosis. Therefore, the aim of the present study is to examine the role of personality factors as predictors of fatigue, quality of life, prognosis, and health care consumption in sarcoidosis and pulmonary fibrosis. In this study a number of possible moderators, such as social support, will also be examined, aiming to get a full picture of the relationship between the various factors examined. Known and new sarcoidosis and pulmonary fibrosis patients (inclusion period 1 year) of ild care team of the outpatient clinic of the department of Respiratory Medicine of the University Hospital Maastricht will be asked to participate through completing questionnaires at baseline and every six months for 18 months, and allowing the researchers access to their medical records for the purpose of this study.

Conditions

Sarcoidosis; Pulmonary Fibrosis

Study Design

• Study Time Perspective: CROSS_SECTIONAL

Study Groups

sarcoidosis

Sarcoidosis known by the ild care team of the outpatient clinic of the department of Respiratory Medicine of the University Hospital Maastricht as well as new patients attending the out-patient clinic from August 2007 to January 2009

No interventions assigned to this group

pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) patients known by the ild care team of the outpatient clinic of the department of Respiratory Medicine of the University Hospital Maastricht as well as new patients attending the out-patient clinic from August 2007 to January 2009

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Patients have to be diagnosed with sarcoidosis based on consistent clinical features and BAL fluid analysis results, according to the WASOG guidelines.
• The diagnosis IPF will be made based on the ATS guidelines

Exclusion Criteria

• Poor expression in the Dutch language
• Relevant co morbidity such as a malignancy, dementia, and a history of psychiatric illness

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tilburg University

OTHER

Sponsor Role: collaborator

Maastricht University Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Marjolein Drent, Md, PhD

Role: STUDY_CHAIR

Maastricht University

Jolanda de Vries, PhD

Role: STUDY_CHAIR

Tilburg University

Marjon Elfferich, MSc

Role: PRINCIPAL_INVESTIGATOR

Gelderse Vallei Ziekenhuis Ede

References

Elfferich MD, De Vries J, Drent M. Type D or 'distressed' personality in sarcoidosis and idiopathic pulmonary fibrosis. Sarcoidosis Vasc Diffuse Lung Dis. 2011 Jul;28(1):65-71.

Reference Type: RESULT

PMID: 21796893 (View on PubMed)

Other Identifiers

MEC 07-4-015

Identifier Type: -

Identifier Source: org_study_id