Phase I Study of AZD2171 co-Administered With Fixed Multiple Oral Doses of ZD1839 in Patients With Advanced Cancer

NCT ID: NCT00502060

Last Updated: 2009-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

65 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-08-31

Study Completion Date

2006-06-30

Brief Summary

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Phase I AZD2171 in combination with ZD1839 study recruiting patients with advanced cancer

Detailed Description

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Conditions

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Advanced Tumor

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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AZD2171

Intervention Type DRUG

ZD1839

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* tumor progressed on standard therapy or ineligible for standard therapy
* life expectancy of 12 weeks or more
* WHO performance status 0-2

Exclusion Criteria

* History of active interstitial lung disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AstraZeneca

INDUSTRY

Sponsor Role lead

Principal Investigators

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Nick Botwood, BSc, MBBS, MRCP, MFPM

Role: STUDY_DIRECTOR

AstraZeneca

G Giaccone, Prof

Role: PRINCIPAL_INVESTIGATOR

Vrije Universiteit Medical Centre

Locations

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Research Site

Amsterdam, , Netherlands

Site Status

Research Site

Nijmegen, , Netherlands

Site Status

Research Site

Utrecht, , Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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D8480C00004

Identifier Type: -

Identifier Source: org_study_id

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