Phase I, Open-Label, Dose-Escalation Study of AZD4877 in Solid Tumors

NCT ID: NCT00389389

Last Updated: 2009-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-09-30

Study Completion Date

2008-10-31

Brief Summary

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The primary purpose of this study is to find out what the maximum tolerated dose is for an experimental drug called AZD4877 based on the side effects experiences by patients that receive AZD4877 on a weekly basis

Detailed Description

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Conditions

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Neoplasms

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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AZD4877

intravenous infusion

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Advanced solid tumors for which standard treatment doesn't exist or is no longer effective.
* Relatively good overall health other than your cancer.

Exclusion Criteria

* Poor bone marrow function (not producing enough blood cells).
* Serious heart conditions.
* Poor liver or kidney function.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AstraZeneca

INDUSTRY

Sponsor Role lead

Principal Investigators

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Judith Ochs, MD

Role: STUDY_DIRECTOR

AstraZeneca

Locations

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Research Site

Denver, Colorado, United States

Site Status

Research Site

Nashville, Tennessee, United States

Site Status

Research Site

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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D2782C00001

Identifier Type: -

Identifier Source: org_study_id

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