AZD1152 in Patients With Advanced Solid Malignancies-Study 3

NCT ID: NCT00497679

Last Updated: 2009-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE1

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-08-31

Study Completion Date

2007-07-31

Brief Summary

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The primary purpose of this protocol is to investigate the safety and tolerability of AZD1152 when given as a continuous 7-day infusion every week and every 2 weeks in patients with advanced solid malignancies.

Detailed Description

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Conditions

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Solid Tumours

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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AZD1152

7-day continuous intravenous infusion

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Histological or cytological confirmation of a solid, malignant tumour

Exclusion Criteria

* Participation in an investigational drug study within 21 days prior to entry or who have not recovered from the effects of an investigational study drug
* Treatment with radiotherapy/chemotherapy with 4 weeks of first dose
* Recent major surgery within 4 weeks prior to entry to the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AstraZeneca

INDUSTRY

Sponsor Role lead

Principal Investigators

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David Kerr, MD

Role: PRINCIPAL_INVESTIGATOR

University of Oxford

Locations

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Research Site

Manchester, , United Kingdom

Site Status

Research Site

Newcastle, , United Kingdom

Site Status

Research Site

Oxford, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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EudraCT: 2005-004244-31

Identifier Type: -

Identifier Source: secondary_id

D1531C00003

Identifier Type: -

Identifier Source: org_study_id

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