EMRI SureScan™ Clinical Study

NCT ID: NCT00433654

Last Updated: 2025-09-15

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

484 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-02-28

Study Completion Date

2010-08-31

Brief Summary

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The purpose of this clinical study is to confirm safety and efficacy in the clinical magnetic resonance imaging (MRI) environment of the investigational EnRhythm MRI™ SureScan™ Pacing System (used in support of Revo MRI™ SureScan Pacing System launch).

Detailed Description

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This study is a prospective, multi-center global study.

Conditions

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Bradycardia Slow Heart Beat

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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MRI group

The MRI group underwent a one-hour MRI scan at the 9-12 weeks post-implant follow-up.

Group Type ACTIVE_COMPARATOR

Implantable Pulse Generator (IPG) and Pacing Leads (wires)

Intervention Type DEVICE

Pacer and leads

Magnetic Resonance Imaging (MRI) scan

Intervention Type OTHER

One hour MRI scan on the head and lower back.

Control group

The control group waited for one hour (no MRI) at the 9-12 weeks post-implant follow-up.

Group Type OTHER

Implantable Pulse Generator (IPG) and Pacing Leads (wires)

Intervention Type DEVICE

Pacer and leads

Interventions

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Implantable Pulse Generator (IPG) and Pacing Leads (wires)

Pacer and leads

Intervention Type DEVICE

Magnetic Resonance Imaging (MRI) scan

One hour MRI scan on the head and lower back.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subject has, or is at risk of having, a heart beat that is too slow and his/her doctor has determined he/she needs a pacemaker.
* Subject available for follow-up at study center for length of study.
* Subject able and willing to undergo elective MRI scanning without sedation.

Exclusion Criteria

* Subject has, or is at risk of having, a heart beat that is too fast and his/her doctor has determined he/she needs an implantable cardioverter defibrillator (ICD).
* Subject needs or will need another MRI-scan, other than those required by the study, during the required study follow-up period.
* Pregnant women, or women of child bearing potential who are not on a reliable form of birth control.
* Subject who intends to participate in another clinical study during this clinical study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Cardiac Rhythm and Heart Failure

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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EMRI SureScan Clinical Study Team

Role: STUDY_CHAIR

Medtronic

Locations

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Redwood City, California, United States

Site Status

Salinas, California, United States

Site Status

Orlando, Florida, United States

Site Status

Peachtree City, Georgia, United States

Site Status

Des Moines, Iowa, United States

Site Status

Minneapolis, Minnesota, United States

Site Status

Kansas City, Missouri, United States

Site Status

St Louis, Missouri, United States

Site Status

Mineola, New York, United States

Site Status

Cincinnati, Ohio, United States

Site Status

Cleveland, Ohio, United States

Site Status

Erie, Pennsylvania, United States

Site Status

Knoxville, Tennessee, United States

Site Status

Charlottesville, Virginia, United States

Site Status

Norfolk, Virginia, United States

Site Status

Graz, , Austria

Site Status

Linz, , Austria

Site Status

Liège, , Belgium

Site Status

Mons, , Belgium

Site Status

Calgary, Alberta, Canada

Site Status

Victoria, British Columbia, Canada

Site Status

Kingston, Ontario, Canada

Site Status

London, Ontario, Canada

Site Status

Montreal, Quebec, Canada

Site Status

Sainte-Foy, Quebec, Canada

Site Status

Prague, , Czechia

Site Status

Rouen, , France

Site Status

Bad Nauheim, , Germany

Site Status

Bonn, , Germany

Site Status

Dortmund, , Germany

Site Status

Dresden, , Germany

Site Status

Essen, , Germany

Site Status

Göttingen, , Germany

Site Status

Hamburg, , Germany

Site Status

Marburg, , Germany

Site Status

München, , Germany

Site Status

Ulm, , Germany

Site Status

Asti, , Italy

Site Status

Pescia, , Italy

Site Status

Pietra Ligure, , Italy

Site Status

Viterbo, , Italy

Site Status

Amsterdam, , Netherlands

Site Status

Nieuwegein, , Netherlands

Site Status

Zurich, , Switzerland

Site Status

London, , United Kingdom

Site Status

Countries

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United States Austria Belgium Canada Czechia France Germany Italy Netherlands Switzerland United Kingdom

References

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Sutton R, Kanal E, Wilkoff BL, Bello D, Luechinger R, Jenniskens I, Hull M, Sommer T. Safety of magnetic resonance imaging of patients with a new Medtronic EnRhythm MRI SureScan pacing system: clinical study design. Trials. 2008 Dec 2;9:68. doi: 10.1186/1745-6215-9-68.

Reference Type DERIVED
PMID: 19055703 (View on PubMed)

Other Identifiers

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212

Identifier Type: -

Identifier Source: org_study_id

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