INGEVITY+ Active Fixation Pace/Sense Lead Clinical Study

NCT ID: NCT04346537

Last Updated: 2022-07-14

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

109 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-06

Study Completion Date

2021-03-01

Brief Summary

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The objective of this study is it to confirm the safety and effectiveness of the INGEVITY+ Active Fixation Pace/Sense Lead.

Detailed Description

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Conditions

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Bradycardia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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INGEVITY+™ Pace/Sense Lead

The INGEVITY+ lead is indicated for chronic pacing and sensing in the right atrium and/or right ventricle when used with a compatible pulse generator.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject is willing and capable of providing informed consent
2. Subject is intended to undergo initial (de novo) pacing system implant using INGEVITY+ Leads in the Right Atrium (RA) and Right Ventricle (RV) and a Boston Scientific pulse generator
3. Subject meets an indication for a Boston Scientific Pacemaker or CRT-P device per product labeling (Physician's Technical Manual)
4. Willing and capable of participating in all testing/visits associated with this clinical study at an approved clinical study center and at the intervals defined by this protocol
5. Age 18 or above, or of legal age to give informed consent specific to state and national law

Exclusion Criteria

1. Known or suspected sensitivity to dexamethasone acetate (DXA)
2. Has a mechanical tricuspid heart valve
3. Women of childbearing potential who are or might be pregnant at the time of study enrollment or INGEVITY+ Lead implant (method of assessment upon physician's discretion)
4. Currently requiring hemo- or peritoneal dialysis
5. Subject has or has had implanted any pacing or ICD system, including subcutaneous, transvenous or leadless systems
6. Intended to receive a single chamber device
7. Documented history of permanent or persistent AF
8. Currently on an active organ transplant list
9. Documented life expectancy of less than 12 months
10. Enrolled in any other concurrent study unless prior approval is received from the Sponsor
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Devi Nair, MD

Role: PRINCIPAL_INVESTIGATOR

Arrhythmia Research Group

Locations

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Heart Center Research, LLC

Huntsville, Alabama, United States

Site Status

Arrhythmia Research Group

Jonesboro, Arkansas, United States

Site Status

Torrance Memorial Medical Center

Torrance, California, United States

Site Status

Emory University Hospital

Atlanta, Georgia, United States

Site Status

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Site Status

Cardiovascular Institute of Michigan

Clinton Township, Michigan, United States

Site Status

Cox Health

Springfield, Missouri, United States

Site Status

Catholic Medical Center

Manchester, New Hampshire, United States

Site Status

Deborah Heart and Lung

Browns Mills, New Jersey, United States

Site Status

Aultman Hospital

Canton, Ohio, United States

Site Status

Saint Thomas Health

Nashville, Tennessee, United States

Site Status

Sentara Norfolk General Hospital

Norfolk, Virginia, United States

Site Status

PeaceHealth Southwest Medical

Bellingham, Washington, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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92424682

Identifier Type: -

Identifier Source: org_study_id

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