MedDataX Logo

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

NCT ID: NCT00432718

Last Updated: 2007-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

260 participants

Study Classification

INTERVENTIONAL

Study Start Date

2001-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Compare the incidence of ventilator associated pneumonia with or without tracheal isotonic saline instillation before tracheal suctioning

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Ventilator Associated Tracheobronchitis in the First 14 Days in ICU

NCT01802827

Airway Colonization Tracheobronchitis and Pneumonia Associated With Ventilator
COMPLETED

Does Tracheal Suction During Extubation in Intensive Care Unit Decrease Functional Residual Capacity

NCT03681626

Critically Ill Extubation Intensive Care Unit
COMPLETED NA

Single-used Versus MultiPlE-used Endotracheal suCtIon cAtheters in Mechanically ventiLated ICU Patients

NCT06207513

Ventilator Associated Pneumonia
COMPLETED NA

Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients

NCT01807884

Ventilator Acquired Pneumonia Aspiration
COMPLETED NA

Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients

NCT00127621

Respiratory Insufficiency
TERMINATED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mechanical Ventilation Critically Ill Patients

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Saline Instillation before Tracheal Suctioning

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Consecutive patients foreseen to receive mechanical ventilation for more than 72 hours

Exclusion Criteria

* Previous mechanical ventilation in the last month
* Mechanical ventilation for more than 6 hours before arrival at ICU,
* Contraindication to bronchoscopy and
* Be expected to die or undergo withdrawal treatment within 48 hours-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hospital do Cancer, Sao Paulo

OTHER

Sponsor Role lead

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Pedro Caruso, MD

Role: PRINCIPAL_INVESTIGATOR

Intensive Care Unit - Hospital do Câncer and University of Sao Paulo Medical School

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

ICU Hospital do Câncer

São Paulo, São Paulo, Brazil

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Brazil

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

342/01

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy
NCT04642703 UNKNOWN
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
NCT07308171 NOT_YET_RECRUITING NA
Efficacy of Early Tracheostomy to Reduce Incidence of Ventilator Acquired Pneumonia (VAP)
NCT00262431 COMPLETED PHASE3
Clinical Application and Outcome of Non-invasive Ventilation in Different Chest Diseases
NCT03169452 UNKNOWN
Weekly Versus no Routine Ventilator Circuit Changes in NICU
NCT02326207 TERMINATED NA
Prevention of Ventilator-Associated Pneumonia by Automatic Control of the Tracheal Tube Cuff Pressure
NCT00364299 COMPLETED NA
The Effect of Continuous Management of Suction Cuff Pressure and Subglottic Irrigation Suction on Preventing VALRI Study
NCT06867237 NOT_YET_RECRUITING NA
Post -Extubation Respiratory Failure
NCT04441736 COMPLETED NA
Ventilator Inspiratory Trigger Sensitivity Adjustment Versus Threshold Device Training on Pulmonary Functions in Acute Stroke Patients
NCT07003867 COMPLETED NA
Original Protocol of Oral Cavity Care During Long-term Mechanical Ventilation
NCT05146817 UNKNOWN NA
Preoxygenation for Tracheal Aspirations in Intensive Care
NCT06421012 RECRUITING NA
A Feasibility Study of a Low Tidal Volume Ventilation Strategy in One Lung Ventilation
NCT03467607 COMPLETED NA
Effect of Mechanical Ventilation on the Incidence of Pneumothorax After Subclavian Vein Catheterization
NCT01815801 COMPLETED NA
Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial
NCT01150864 COMPLETED NA
Oropharyngeal Aspiration to Reduce Ventilator-Related Pneumonia
NCT04107363 COMPLETED NA
Effect of Three Modalities of Spontaneous Breathing Tests on Respiratory Efforts in Tracheostomized Patients
NCT03856424 UNKNOWN NA
High Flow Nasal Oxygenation Versus Non-invasive Ventilation for Patients With Blunt Chest Trauma
NCT05342103 COMPLETED NA
The Use of Pulmonary Hyperinflation With the Mechanical Ventilator in Cardiac Patients
NCT04583371 UNKNOWN NA
Rapid and Safe Sputum Suction Method Validation
NCT06508008 RECRUITING NA
Reduced Ventilator-Free Days and Bacterial Colonization of Sub-Glottic Secretions
NCT02311296 WITHDRAWN
Breath and Air Stacking on Respiratory Mechanics in Tracheostomized Patients
NCT04012489 COMPLETED NA
High Frequency Percussive Ventilation in Hypersecretive Tracheostomized Patients
NCT05200507 UNKNOWN
Effectiveness of Oropharyngeal Suctioning in Preventing Ventilator-Associated Pneumonia: A Randomized Controlled Trial.
NCT07128537 NOT_YET_RECRUITING NA
Air-impingement Manipulation to Clear Subglottic Secretion to Prevent VAP in Prolonged Intubated Patients
NCT02632539 UNKNOWN PHASE3
High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma
NCT05527431 COMPLETED NA