Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial
NCT ID: NCT01150864
Last Updated: 2017-05-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
190 participants
INTERVENTIONAL
2010-04-30
2017-03-31
Brief Summary
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1. Passive and Active-Passive airway conditioning devices reduce the incidence of ventilator associated pneumonia
2. Active-Passive airway conditioning devices reduce the incidence of endotracheal tube obstruction
3. Nurses' workload is reduced with Passive and Active-Passive airway conditioning devices
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Passive Humidifier
The Passive Humidifier (HME)will changed every 24 hours
Airway Conditioning
Each Passive device will be changed daily. When using Active and Passive devices as well as Active-Passive devices the ventilatory circuit will be changed every 7 days.
Active-Passive humidifier
The Active-Passive Humidifier will be changed every 24 hours
Airway Conditioning
Each Passive device will be changed daily. When using Active and Passive devices as well as Active-Passive devices the ventilatory circuit will be changed every 7 days.
Hot Water Humidifier
Hot water humidifier will be set at 36-37 °C
Airway Conditioning
Each Passive device will be changed daily. When using Active and Passive devices as well as Active-Passive devices the ventilatory circuit will be changed every 7 days.
Interventions
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Airway Conditioning
Each Passive device will be changed daily. When using Active and Passive devices as well as Active-Passive devices the ventilatory circuit will be changed every 7 days.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age higher than 18 years
* Invasive mechanical ventilation
* Endotracheal intubation or tracheostomy for more than 24 hours
Exclusion Criteria
* Severe ARDS (PaO2/FiO2 lower than 100, or PaCO2 higher than 60 mmHg)
* Inefficient cough
* Head Trauma
* Spinal cervical trauma
* Chest trauma
* Pregnancy
* Expectance of poor survival within 72 hours
* Congenital airway disease
* Immunosuppression
* Supraglottic aspiration devices
18 Years
90 Years
ALL
No
Sponsors
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Università degli Studi dell'Insubria
OTHER
Responsible Party
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Paolo Severgnini
MD
Principal Investigators
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Paolo Pelosi, MD
Role: STUDY_DIRECTOR
Universita' degli Studi dell'Insubria, Varese, Italy
Paolo Severgnini, MD
Role: PRINCIPAL_INVESTIGATOR
University of Insubria, Varese, Italy
Locations
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Ospedale di Circolo
Varese, , Italy
Countries
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Other Identifiers
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0001069
Identifier Type: -
Identifier Source: org_study_id
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