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Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment

NCT ID: NCT00414479

Last Updated: 2010-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-07-31

Study Completion Date

2010-01-31

Brief Summary

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The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).

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Detailed Description

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The study will be carried out in an area around Lake Victoria in Kenya where the prevalence of schistosomiasis and malaria are highest in the areas nearest to the Lake. Depending on the prevalence of schistosomiasis a sample of between 876 to 2.524 children will be enrolled in the study. The children who will be in the age between 9 to 12 year, will have their stool and urine examined for schistosomiasis and intestinal worms and a blood sample will be examined for malaria parasites and the hemoglobin level. Children will also be weight, measured and examined by a doctor and register their food intake over one week, to determine their nutritional status. Children who are found to be infected with schistosomiasis, intestinal worms or malaria will be offered treatment. Children who are found to have anemia will be offered a course of iron supplementation, children with severe anemia will be referred to the nearest health facility for treatment. 12 months after the initial examinations and treatment all children will have a re-examination of their stool, urine and blood.

Conditions

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Anaemia Schistosomiasis Infection Malaria Iron Deficiency

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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children 9-12 years of age

Children with schistosomiasis, malaria and anaemia

praziquantl, iron, ACT

Intervention Type DRUG

Interventions

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praziquantl, iron, ACT

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* school children between 9 to 12 year
Minimum Eligible Age

9 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DBL -Institute for Health Research and Development

OTHER

Sponsor Role lead

Principal Investigators

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Diana Karanja, DR

Role: PRINCIPAL_INVESTIGATOR

Kenya Medical Research Institute

Locations

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Kenya Medical Research Institute

Kisumu, , Kenya

Site Status

Countries

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Kenya

Other Identifiers

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SRP-KY-DK-06

Identifier Type: -

Identifier Source: org_study_id

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