Schistosomiasis in Formal and Non-Formal Schools in Uganda: Implications for Control Programmes

NCT ID: NCT00463593

Last Updated: 2008-01-25

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 1293 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2006-12-31
• Study Completion Date: 2007-06-30

Brief Summary

Current efforts to control schistosomiasis and soil-transmitted helminthes infections focus on the school-age population, and school-based treatment delivery programs offer a major cost advantages because of the use of the existing school infrastructure and the fact that schoolchildren are accessible through schools. However, in many developing countries, large numbers of school-age children are not in school and this has raised questions about the effectiveness of school-based programs in reaching non-enrolled children. Increasingly, the non-formal education sector is providing a growing solution to the problem of poor enrolment in basic education, especially in sub-Saharan Africa, and has recently been used to deliver praziquantel as part of a national schistosomiasis control program in Uganda. However, it is unclear how effective this program has been in reaching children who attend non-formal schools and whether the program has been reaching children from the poorest households.

Detailed Description

This study will compare infection and nutritional status of children enrolled in formal schools and non-formal schools, and non-enrolled children in Nakasongola District in Uganda, and investigate the process and impact of treatment delivered by the national control program. The study will consist of household surveys and cross-sectional parasitological and hematological surveys, with follow-up six months later. The evaluation will take place over the course of a year and will:

• Compare the infection and nutritional status of children enrolled in formal schools and non-formal schools, and non-enrolled children in Nakasongola District, Uganda
• Compare programmatic process indicators, including enrolment rates, attendance rates, access to water and sanitation, treatment coverage in formal and non-formal schools
• Investigate the impact of treatment on intensity of infection and reinfection rates in formal and non-formal schools.

Conditions

Schistosomiasis; Helminthiasis; Anaemia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

2

children enrolled in formal schools and children not enrolled in formal schools

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• School children in grad 1 and 2

• Minimum Eligible Age: 6 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

DBL -Institute for Health Research and Development

OTHER

Sponsor Role: lead

Principal Investigators

Narcis Kabatereine, Dr

Role: PRINCIPAL_INVESTIGATOR

Vector Control Division, Ministry of Health Uganda

Locations

Vector Control Division

Kampala, , Uganda

Countries

Uganda

Other Identifiers

SRP-UG-NK-06

Identifier Type: -

Identifier Source: org_study_id