Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls

NCT ID: NCT00406263

Last Updated: 2016-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

49 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-11-30

Study Completion Date

2010-10-31

Brief Summary

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Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear. The objective of this trial is to evaluate and compare the level and progression of cataract advancement in controls versus eyes that have undergone 20-gauge pars plana vitrectomy and 25-gauge pars plana vitrectomy.

Detailed Description

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Approximately 105 patients will be recruited to obtain 35 control eyes that have not had pars plana vitrectomy and 35 eyes who will have undergone 20-gauge pars plana vitrectomy and 35 eyes will have undergone 25-gauge pars plana vitrectomy. Scheimpflug crystalline lens photographs will be taken for evaluation of level and progression of cataract development.

Conditions

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Nuclear Sclerotic Cataract

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Scheimpflug crystalline lens photographs

scheimpflug photographs

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* phakic eyes of patients that are scheduled to undergo pars plana vitrectomy,
* controls will be phakic eyes of patients that have not undergone andy kind of intraocular surgery,
* age 18 and older

Exclusion Criteria

* any eye that is pseudophakic,
* has had previous vitreoretinal surgery,
* has had previous intravitreal injection,
* previous intraocular inflammatory condition such as uveitis,
* previous irradiation,
* any patient with a history of ocular malignancy,
* history of infectious intraocular condition
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Barnes Retina Institute

OTHER

Sponsor Role lead

Responsible Party

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Rhonda Weeks

Nancy Holekamp, MD, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nancy M Holekamp, MD

Role: PRINCIPAL_INVESTIGATOR

Barnes Retina Institute

Locations

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Barnes Retina Institute

St Louis, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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06-1016

Identifier Type: -

Identifier Source: org_study_id

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