Outcome Following Phacoemulsification Versus Small Incision Cataract Surgery (SICS)

NCT ID: NCT00821223

Last Updated: 2010-05-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

420 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-02-28

Study Completion Date

2010-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Hypothesis :

Phacoemulsification is superior to SICS with regards to:

* Immediate unaided high and low contrast visual performance
* Its impact on quality of life.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Phacoemulsification procedure

* Infiniti Vision System with Software 2.03 or higher, OZil handpiece (HP)
* Anaesthesia: topical
* Incision: temporal clear corneal 2.2 mm single plane
* CCC and hydrodissection, sculpting and division using step by step chop in situ and lateral separation, I/A.
* Single-piece AcrySof IOL (SN60WF) in the bag

SICS procedure

* Anaesthesia: peribulbar
* Incision: superior scleral tunnel 6.5 to 7 mm
* CCC and hydrodissection
* Nuclear expression: blumenthal technique using anterior chamber maintainer, manual cortical clean-up
* Single-piece PMMA (MZ60BD) in the bag

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Visual Outcomes Quality of Life

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

manual small incision cataract surgery

surgical intervention by small incision cataract surgery

Group Type ACTIVE_COMPARATOR

manual small incision surgery

Intervention Type PROCEDURE

phacoemulsification

surgical intervention by phacoemulsification

Group Type OTHER

phacoemulsification and SICS

Intervention Type PROCEDURE

SICS with rigid IOL implantation Phaco with foldable IOL implantation

phacoemulsification

Intervention Type PROCEDURE

cataract surgery

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

phacoemulsification and SICS

SICS with rigid IOL implantation Phaco with foldable IOL implantation

Intervention Type PROCEDURE

manual small incision surgery

Intervention Type PROCEDURE

phacoemulsification

cataract surgery

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

ECCE Manual SICS exrtracapsular cataract surgery extracapsualr cataract surgery

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Prospective subjects should be diagnosed with senile cataract. Subject must require extraction of cataract in one eye followed by implantation of an AcrySof (SN60WF) or PMMA (MZ60BD) posterior chamber intraocular lens.
* Pupil dilation equal or greater to 7 mm after mydriasis.
* Patients undergoing cataract surgery for the first eye.
* Visual prognosis equal or greater to 6/12.

Exclusion Criteria

* Patients with history of ocular pathology, glaucoma, uveitis, high myopia, PEX, or corneal pathology.
* Patients with traumatic, subluxated and posterior polar cataract.
* Patients who had previously ocular surgery in the past 6 months prior to the screening visit.
* Patients with diabetic retinopathy.
* Patients who are not suitable for follow-up visits.
* Patients with Fuchs' Dystrophy, Macular Degeneration, Ocular Surface Disease that will interfere with normal recovery.
* Any patients with significant intra-operative complications will be removed from the overall analysis of the results. All patient data should still be recorded, even if from the "excluded" patient group.
Minimum Eligible Age

50 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Iladevi Cataract and IOL Research Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Iladevi Cataract and IOL Research Center, Ahmedabad, India

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Alpesh R Shah, Dr

Role: PRINCIPAL_INVESTIGATOR

Iladevi Cataract and IOL Research Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

S. K. Red Cross Eye Hospital,

Dholka, Gujarat, India

Site Status

Countries

Review the countries where the study has at least one active or historical site.

India

References

Explore related publications, articles, or registry entries linked to this study.

Gogate P, Deshpande M, Nirmalan PK. Why do phacoemulsification? Manual small-incision cataract surgery is almost as effective, but less expensive. Ophthalmology. 2007 May;114(5):965-8. doi: 10.1016/j.ophtha.2006.08.057. Epub 2007 Feb 12.

Reference Type RESULT
PMID: 17296230 (View on PubMed)

Ruit S, Tabin G, Chang D, Bajracharya L, Kline DC, Richheimer W, Shrestha M, Paudyal G. A prospective randomized clinical trial of phacoemulsification vs manual sutureless small-incision extracapsular cataract surgery in Nepal. Am J Ophthalmol. 2007 Jan;143(1):32-38. doi: 10.1016/j.ajo.2006.07.023. Epub 2006 Sep 5.

Reference Type RESULT
PMID: 17188040 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

009

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.