Does Implant Design Improve Postoperative Flexion?

NCT ID: NCT00380861

Last Updated: 2023-07-24

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

93 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-01

Study Completion Date

2009-12-01

Brief Summary

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This study will evaluate whether design features of one implant design allows more knee bend than the other. Patients will have 1 design in the left knee and 1 design in their right knee. Both knee surgeries will be on the same day.

Detailed Description

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The primary objective of this study is to determine whether the passive, non-weight-bearing flexion is superior with the posterior-stabilized PFC® Sigma™ RP-F compared to the posterior-stabilized PFC® Sigma™ RP in bilateral Subjects receiving both implants and if this difference is a function of implant design.

Conditions

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Non-inflammatory Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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PFC Sigma RP-F

PFC® Sigma™ RP-F knee implant is a posterior stabilized cemented component cemented that is implanted with a standard posterior stabilized surgical technique.

Group Type ACTIVE_COMPARATOR

Total knee replacement using the PFC Sigma RPF knee implant.

Intervention Type DEVICE

Total knee replacement

PFC Sigma RP

P.F.C.® Sigma™ Rotating Platform (RP) Cruciate Retaining Knee System has a special insert that helps the knee move more like it did before the knee replacement.

Group Type ACTIVE_COMPARATOR

Total knee replacement using the PFC Sigma RP knee implant

Intervention Type DEVICE

Total knee replacement

Interventions

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Total knee replacement using the PFC Sigma RPF knee implant.

Total knee replacement

Intervention Type DEVICE

Total knee replacement using the PFC Sigma RP knee implant

Total knee replacement

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Non-Inflammatory Arthritis
* Age = 40-70 years
* Male or female
* Suitable for devices in study
* Needing primary simultaneous bilateral knee replacements
* Willing to consent and authorize release of personal health information
* Subjects who are able to understand this clinical investigation, co-operate with investigational procedures and are willing to return to the clinic, hospital and predefined physical therapy centers for all the required postoperative follow-ups,

Exclusion Criteria

* Existing conditions that would compromise participation
* Multiple joint involvement
* Pregnant/lactating women
* Inflammatory arthritis
* Fixed flexion contracture greater than 20 degrees
* Previous knee replacement of any type
* Needing device(s) not specified in protocol
* The Subject is a known drug or alcohol abuser or has a psychological disorder that would compromise follow-up
* Those who have participated in an investigation in the last 3 months
* Those involved in personal injury litigation, medical-legal or workers compensation claims
* Failure to follow surgical technique details specified in the protocol
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DePuy Orthopaedics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tammy O'Dell, EMT, CCRA, CCRC

Role: STUDY_DIRECTOR

DePuy Orthopaedics

Locations

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Doug Dennis

Denver, Colorado, United States

Site Status

Heekin Orthopaedics

Jacksonville, Florida, United States

Site Status

University of Iowa Hospital & Clinic Dept. of Orthopaedic Surgery

Iowa City, Iowa, United States

Site Status

Lakewood Orthopaedic Surgeons

Lakewood, Washington, United States

Site Status

Countries

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United States

References

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Tippett SR, Mang J, Dwyer KA, Lesko J, O'Dell T. Collecting data with Palm technology: comparing preoperative expectations and postoperative satisfaction in patients undergoing total knee arthroplasty. J Bone Joint Surg Am. 2010 Dec;92 Suppl 2:59-67. doi: 10.2106/JBJS.J.00827. No abstract available.

Reference Type DERIVED
PMID: 21123592 (View on PubMed)

Other Identifiers

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04092

Identifier Type: -

Identifier Source: org_study_id

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