Glucose Control in Open Heart Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-10-31

Study Completion Date

2004-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to seek if there is difference to state glucose level in 80-120mg/dl or 200mg/dl in patients submitted to open heart surgery

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Comparing Blood Glucose Control Intraoperative Between Insulin Drip vs. Insulin Boluses Will Provide Valuable Information on the Optimal Method for Achieving Blood Glucose Control Intraoperatively.

NCT07056088

Hypoglycemia (Diabetic)

NOT_YET_RECRUITING NA

Perioperative Versus Postoperative Glycemia Control in Cardiac Surgery Patients

NCT01548963

Perioperative and Postoperative Hyperglycemia Tight Glycemia Control

COMPLETED NA

Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery

NCT00328094

Peripheral Vascular Disease Abdominal Aortic Aneurysm

TERMINATED NA

Comparison of Three Protocols for Tight Glycemic Control in Cardiac Surgery Patients

NCT00764712

Hyperglycemia

COMPLETED NA

Glycemic Variability and Autonomic Nervous System in Cardiac Surgery Patients

NCT05454735

Blood Glucose Variability Cardiac Surgical Procedures Autonomic Nervous System

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Hyperglycaemia in the intensive care unit and perioperative period has been accused to be one of the causes of worse clinical outcome. It is known that in open heart surgeries the glucose level must be set less than 200mg/dl, but new trials had set the glucose level lower than that: 140mg/dl in some studies and even lower (80-110mg/dl). Our trial had the intention to seek if there is difference setting glucose level in 2 different ones would modifies clinical outcome.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hyperglycaemia During Perioperative Period Heart Valve Diseases Ventricular Dysfunction

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

human regular insulin

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* adult more than 21 years old
* open heart surgery with cardiopulmonary bypass

Exclusion Criteria

* renal dysfunction
* reoperation
* use of inotropic support
* neurological dysfunction
* chronic pulmonary obstructive disease
* emergency or urgency

Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No