Use of Cone Beam Kilovoltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer

NCT ID: NCT00358007

Last Updated: 2025-05-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-03-31

Study Completion Date

2010-09-30

Brief Summary

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To evaluate the use of cone beam computed tomography in treating head and neck to hopefully reduce side effects

Detailed Description

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The general purpose of this study is to evaluate Kilovoltage (kv) Imaging, specifically the Cone-beam CT (CBCT) scan device, to assess the accuracy of radiation therapy treatment delivery for patients with head and neck neoplasms

Conditions

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Head and Neck Neoplasms

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Cone Beam CT

Group Type EXPERIMENTAL

PTV Reduction

Intervention Type DEVICE

The margin around the area to be treated with radiation is decreased due the image guidance of the cone beam CT

Interventions

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PTV Reduction

The margin around the area to be treated with radiation is decreased due the image guidance of the cone beam CT

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* any patient receiving radiation therapy for a head and neck tumor assigned to the new Elekta Synergy Linare Accelerator

Exclusion Criteria

* NA
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sidney Kimmel Cancer Center at Thomas Jefferson University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pramila Rani Anne, MD

Role: PRINCIPAL_INVESTIGATOR

Thomas Jefferson University

Locations

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Thomas Jefferson University

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

References

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Den RB, Doemer A, Kubicek G, Bednarz G, Galvin JM, Keane WM, Xiao Y, Machtay M. Daily image guidance with cone-beam computed tomography for head-and-neck cancer intensity-modulated radiotherapy: a prospective study. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1353-9. doi: 10.1016/j.ijrobp.2009.03.059. Epub 2009 Jun 18.

Reference Type RESULT
PMID: 19540071 (View on PubMed)

Related Links

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http://www.KimmelCancerCenter.org

Kimmel Cancer Center at Thomas Jefferson University, an NCI-Designated Cancer Center

Other Identifiers

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2006-10

Identifier Type: OTHER

Identifier Source: secondary_id

JT 1153

Identifier Type: OTHER

Identifier Source: secondary_id

06U.195

Identifier Type: -

Identifier Source: org_study_id

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