Whole-Neck Computed Tomography Perfusion Scan in Imaging Patients With Head and Neck Tumors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

49 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-20

Study Completion Date

2021-06-14

Brief Summary

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This pilot clinical trial studies how well whole-neck computed tomography perfusion scans work in imaging patients with head and neck tumors. Diagnostic imaging procedures, such as whole-neck computed tomography perfusions scans, may provide more information about the blood supply to head and neck tumors which may help doctors plan better treatment.

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Detailed Description

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PRIMARY OBJECTIVES:

I. To assess the difference in whole-neck computed tomography perfusion (WNCTP) parameters (blood volume \[BV\], blood flow \[BF\], capillary permeability \[CP\] and mean transit time \[MTT\]) between head and neck tumor masses (benign or malignant) and adjacent normal skeletal muscle within the same patient.

II. To assess whether the difference in WNCTP parameters between tumor masses and adjacent normal skeletal muscle is different between patients with benign tumor versus (vs.) malignant tumor.

III. To assess the correlation in WNCTP parameters between tumor masses and adjacent normal skeletal muscle.

IV. Determine if more suspicious cervical lymph nodes will be seen using the whole-neck coverage employed in WNCTP compared to the limited coverage of traditional neck CTP.

OUTLINE:

Patients undergo WNCTP scan over 2-3 minutes during standard of care computed tomography (CT).

After completion of study, patients are followed up within 2 days.

Conditions

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Head and Neck Neoplasm Malignant Head and Neck Neoplasm

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Diagnostic (WNCTP scan)

Patients undergo WNCTP scan over 2-3 minutes during standard of care CT.

Computed Tomography Perfusion Imaging

Intervention Type RADIATION

Undergo WNCTP scan

Interventions

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Computed Tomography Perfusion Imaging

Undergo WNCTP scan

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Confirmed or suspected head and neck tumor (benign or malignant)
* Scheduled for contrast CT (standard of care)
* No known allergies to contrast material