Neuroendocrine Dysfunction in Traumatic Brain Injury: Correlation With Cognitive Dysfunction and Repair

NCT ID: NCT00336726

Last Updated: 2011-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Study Classification

OBSERVATIONAL

Brief Summary

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Traumatic Brain Injury (TBI) is a neurologic disorder cuased by physical trauma to the brain. Neuroendocrine abnormalities in these patients have been reported, including central hypogonadism within hours of the insult and eventual recovery of the hypothalamic-pituitary-gonadal axis with recovery of cognitive function to baseline. This pilot study will measure hormonal level of neuroendocine function at the time of TBI and various time points during recovery.

Detailed Description

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Conditions

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Traumatic Brain Injury

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Male subjects having had a recent traumatic brain injury.

Exclusion Criteria

* Currently receivng sex steroids, glucocorticoids, or have an inability to complete the neurobehavioral assessment.
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Denver Research Institute

OTHER

Sponsor Role lead

Responsible Party

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VA Medical Center

Principal Investigators

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Margaret E Wierman, MD

Role: PRINCIPAL_INVESTIGATOR

Dept. of Veterans Affairs/University of Colorado HSC

Other Identifiers

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GR-735

Identifier Type: -

Identifier Source: org_study_id

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