Effects of Endocrine Health on Mental Performance of Men and Women Using Drugs

NCT ID: NCT00245531

Last Updated: 2015-04-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-08-31

Study Completion Date

2010-12-31

Brief Summary

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The purpose of this study is to understand the effects of decreased functioning of the testes or ovaries on mental performance in males and females using illicit drugs excluding marijuana.

Detailed Description

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This research is being done to understand the effects of endocrine abnormalities, specifically hypogonadism (decreased functioning of the testes or ovaries) on cognitive (mental) performance in males and females using illicit drugs (excluding marijuana).

Conditions

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Human Immunodeficiency Virus Positive or Negative

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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+IDU/+HIV or -HIV

No interventions assigned to this group

-IDU and -HIV (controls)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Completed the 8th grade

Exclusion Criteria

* Did not complete the 8th grade. Have a hormone problem for which you are taking medication e.g. testosterone or thyroid medicine, steroids, oral contraceptives, progesterone. Diagnosed with cancer. History of schizophrenia. Currently have or have been diagnosed in the past with meningitis or encephalitis.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

Johns Hopkins University

OTHER

Sponsor Role lead

Responsible Party

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Adrian S. Dobs

Professor of Medicine and Oncology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Adrian S Dobs, M.D.

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

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Johns Hopkins University, The Clinical Trials Unit

Baltimore, Maryland, United States

Site Status

Countries

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United States

References

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Goldberg CS, Trachtenberg F, William Gaynor J, Mahle WT, Ravishankar C, Schwartz SM, Cnota JF, Ohye RG, Gongwer R, Taylor M, Paridon S, Frommelt PC, Afton K, Atz AM, Burns KM, Detterich JA, Hill KD, Cabrera AG, Lewis AB, Pizarro C, Shah A, Sharma B, Newburger JW; Pediatric Heart Network Investigators. Longitudinal Follow-Up of Children With HLHS and Association Between Norwood Shunt Type and Long-Term Outcomes: The SVR III Study. Circulation. 2023 Oct 24;148(17):1330-1339. doi: 10.1161/CIRCULATIONAHA.123.065192. Epub 2023 Oct 5.

Reference Type DERIVED
PMID: 37795623 (View on PubMed)

Zilbermint MF, Wisniewski AB, Xu X, Selnes OA, Dobs AS. Relationship between sex hormones and cognitive performance in men with substance use. Drug Alcohol Depend. 2013 Mar 1;128(3):250-4. doi: 10.1016/j.drugalcdep.2012.08.024. Epub 2012 Sep 26.

Reference Type DERIVED
PMID: 23021515 (View on PubMed)

Other Identifiers

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05-01-12-04

Identifier Type: -

Identifier Source: org_study_id

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